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Vitamin C 3 of 3 : << back


[Antioxidant properties | Immune system]
[Collagen and connective tissue | Hormones | Nervous system]
[Other Functions | Absorption & metabolism | Deficiency | Sources]
[RDA | Supplements | Therapeutic uses]
[Interactions w/ other nutrients | References]

References

  1. Enstrom JE, Kanim LE, Klein MA. Vitamin C intake and mortality among a sample of the United States population. Epidemiology 1992 May; 3(3):194-202
  2. Johnston CS; Solomon RE; Corte C Vitamin C status of a campus population: college students get a C minus. J Am Coll Health, 1998 Mar, 46:5, 209-13
  3. Sahyoun NR; Jacques PF; Russell RM Carotenoids, vitamins C and E, and mortality in an elderly population. Am J Epidemiol, 1996 Sep, 144:5, 501-11
  4. Gey KF; Stähelin HB; Eichholzer M Poor plasma status of carotene and vitamin C is associated with higher mortality from ischemic heart disease and stroke: Basel Prospective Study. Clin Investig, 1993 Jan, 71:1, 3-6
  5. Gale CR; Martyn CN; Winter PD; Cooper C Vitamin C and risk of death from stroke and coronary heart disease in cohort of elderly people. BMJ, 1995 Jun, 310:6994, 1563-6
  6. Nyyssönen K; Parviainen MT; Salonen R; Tuomilehto J; Salonen JT. Vitamin C deficiency and risk of myocardial infarction: prospective population study of men from eastern Finland. BMJ, 1997 Mar, 314:7081, 634-8
  7. Rimm EB; Stampfer MJ; Ascherio A; Giovannucci E; Colditz GA; Willett WC Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med, 1993 May 20, 328:20, 1450-6
  8. Stampfer MJ; Hennekens CH; Manson JE; Colditz GA; Rosner B; Willett WC Vitamin E consumption and the risk of coronary disease in women. N Engl J Med, 1993 May 20, 328:20, 1444-9
  9. Ness AR; Khaw KT; Bingham S; Day NE Vitamin C status and undiagnosed angina. J Cardiovasc Risk, 1996 Aug, 3:4, 373-7
  10. Ness AR; Khaw KT; Bingham S; Day NE Vitamin C status and serum lipids. Eur J Clin Nutr, 1996 Nov, 50:11, 724-9
  11. Hallfrisch J; Singh VN; Muller DC; Baldwin H; Bannon ME; Andres R. High plasma vitamin C associated with high plasma HDL- and HDL2 cholesterol. Am J Clin Nutr, 1994 Jul, 60:1, 100-5
  12. Ness AR; Khaw KT; Bingham S; Day NE Vitamin C status and blood pressure. J Hypertens, 1996 Apr, 14:4, 503-8
  13. Block G Vitamin C and cancer prevention: the epidemiologic evidence. Am J Clin Nutr, 1991 Jan, 53:1 Suppl, 270S-282S
  14. Pandey DK; Shekelle R; Selwyn BJ; Tangney C; Stamler J. Dietary vitamin C and beta-carotene and risk of death in middle-aged men. The Western Electric Study. Am J Epidemiol, 1995 Dec, 142:12, 1269-78
  15. Daviglus ML; Dyer AR; Persky V; Chavez N; Drum M; Goldberg J; Liu K; Morris DK; Shekelle RB; Stamler J Dietary beta-carotene, vitamin C, and risk of prostate cancer: results from the Western Electric Study. Epidemiology, 1996 Sep, 7:5, 472-7
  16. Ocké MC; Kromhout D; Menotti A; Aravanis C; Blackburn H; Buzina R; Fidanza F; Jansen A; Nedeljkovic S; Nissienen A; et al. Average intake of anti-oxidant (pro)vitamins and subsequent cancer mortality in the 16 cohorts of the Seven Countries Study. Int J Cancer, 1995 May, 61:4, 480-4
  17. La Vecchia C; Ferraroni M; DAvanzo B; Decarli A; Franceschi S Selected micronutrient intake and the risk of gastric cancer. Cancer Epidemiol Biomarkers Prev, 1994 Jul, 3:5, 393-8
  18. Ocké MC; Bueno de Mesquita HB; Feskens EJ; van Staveren WA; Kromhout D Repeated measurements of vegetables, fruits, beta-carotene, and vitamins C and E in relation to lung cancer. The Zutphen Study. Am J Epidemiol, 1997 Feb, 145:4, 358-65
  19. Shibata A; Paganini-Hill A; Ross RK; Henderson BE Intake of vegetables, fruits, beta-carotene, vitamin C and vitamin supplements and cancer incidence among the elderly: a prospective study. Br J Cancer, 1992 Oct, 66:4, 673-9
  20. Ferraroni M; La Vecchia C; DAvanzo B; Negri E; Franceschi S; Decarli A Selected micronutrient intake and the risk of colorectal cancer. Br J Cancer, 1994 Dec, 70:6, 1150-5
  21. Jain M; Miller AB; To T. Premorbid diet and the prognosis of women with breast cancer. J Natl Cancer Inst, 1994 Sep, 86:18, 1390-7
  22. Hunter DJ; Manson JE; Colditz GA; Stampfer MJ; Rosner B; Hennekens CH; Speizer FE; Willett WC A prospective study of the intake of vitamins C, E, and A and the risk of breast cancer. N Engl J Med, 1993 Jul 22, 329:4, 234-40
  23. Mares Perlman JA; Brady WE; Klein BE; Klein R; Haus GJ; Palta M; Ritter LL; Shoff SM. Diet and nuclear lens opacities. Am J Epidemiol, 1995 Feb, 141:4, 322-34
  24. Sinclair AJ; Taylor PB; Lunec J; Girling AJ; Barnett AH Low plasma ascorbate levels in patients with type 2 diabetes mellitus consuming adequate dietary vitamin C. Diabet Med, 1994 Nov, 11:9, 893-8
  25. Mayer Davis EJ; Monaco JH; Marshall JA; Rushing J; Juhaeri Vitamin C intake and cardiovascular disease risk factors in persons with non-insulin-dependent diabetes mellitus. From the Insulin Resistance Atherosclerosis Study and the San Luis Valley Diabetes Study. Prev Med, 1997 May, 26:3, 277-83
  26. Ness AR; Khaw KT; Bingham S; Day NE Vitamin C status and respiratory function. Eur J Clin Nutr, 1996 Sep, 50:9, 573-9
  27. Hatch GE Asthma, inhaled oxidants, and dietary antioxidants. Am J Clin Nutr, 1995 Mar, 61:3 Suppl, 625S-630S
  28. Soutar A; Seaton A; Brown K Bronchial reactivity and dietary antioxidants. Thorax, 1997 Feb, 52:2, 166-70
  29. Pfitzenmeyer P; Guilland JC; dAthis P. Vitamin B6 and vitamin C status in elderly patients with infections during hospitalization. Ann Nutr Metab, 1997, 41:6, 344-52
  30. Levine M et al. Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance. Proc Natl Acad Sci U S A, 1996 Apr, 93:8, 3704-9
  31. Blanchard J; Tozer TN; Rowland M Pharmacokinetic perspectives on megadoses of ascorbic acid. Am J Clin Nutr, 1997 Nov, 66:5, 1165-71
  32. Cathcart RF. The method of determining proper doses of vitamin C for the treatment of disease by titrating to bowel tolerance. J Orthomol Psychiat. 1981;10:125-132
  33. Podmore ID; Griffiths HR; Herbert KE; Mistry N; Mistry P; Lunec J. Vitamin C exhibits pro-oxidant properties. Nature, 1998 Apr, 392:6676, 559
  34. Losonczy KG; Harris TB; Havlik RJ Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the Established Populations for Epidemiologic Studies of the Elderly. Am J Clin Nutr, 1996 Aug, 64:2, 190-6
  35. Plotnick GD; Corretti MC; Vogel RA Effect of antioxidant vitamins on the transient impairment of endothelium-dependent brachial artery vasoactivity following a single high-fat meal. JAMA 1997;278:1682-1686
  36. Levine GN; Frei B; Koulouris SN; Gerhard MD; Keaney JF Jr; Vita JA Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation, 1996 Mar, 93:6, 1107-13
  37. Ting HH; Timimi FK; Haley EA; Roddy MA; Ganz P; Creager MA Vitamin C improves endothelium-dependent vasodilation in forearm resistance vessels of humans with hypercholesterolemia. Circulation, 1997 Jun, 95:12, 2617-22
  38. Hornig B; Arakawa N; Kohler C; Drexler H Vitamin C improves endothelial function of conduit arteries in patients with chronic heart failure. Circulation, 1998 Feb, 97:4, 363-8
  39. Dingchao H; Zhiduan Q; Liye H; Xiaodong F The protective effects of high-dose ascorbic acid on myocardium against reperfusion injury during and after cardiopulmonary bypass. Thorac Cardiovasc Surg, 1994 Oct, 42:5, 276-8
  40. Lehr HA; Weyrich AS; Saetzler RK; Jurek A; Arfors KE; Zimmerman GA; Prescott SM; McIntyre TM Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J Clin Invest, 1997 May, 99:10, 2358-64
  41. Weber C; Erl W; Weber K; Weber PC Increased adhesiveness of isolated monocytes to endothelium is prevented by vitamin C intake in smokers. Circulation, 1996 Apr, 93:8, 1488-92
  42. Motoyama T; Kawano H; Kugiyama K; Hirashima O; Ohgushi M; Yoshimura M; Ogawa H; Yasue H Endothelium-dependent vasodilation in the brachial artery is impaired in smokers: effect of vitamin C. Am J Physiol, 1997 Oct, 273:4 Pt 2, H1644-50
  43. Ness AR; Chee D; Elliott P Vitamin C and blood pressure-an overview. J Hum Hypertens, 1997 Jun, 11:6, 343-50
  44. Solzbach U; Hornig B; Jeserich M; Just H Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients. Circulation, 1997 Sep, 96:5, 1513-9
  45. Waring AJ; Drake IM; Schorah CJ; White KL; Lynch DA; Axon AT; Dixon MF Ascorbic acid and total vitamin C concentrations in plasma, gastric juice, and gastrointestinal mucosa: effects of gastritis and oral supplementation. Gut, 1996 Feb, 38:2, 171-6
  46. Zhang HM; Wakisaka N; Maeda O; Yamamoto T. Vitamin C inhibits the growth of a bacterial risk factor for gastric carcinoma: Helicobacter pylori. Cancer, 1997 Nov, 80:10, 1897-903
  47. Paganelli GM; Biasco G; Brandi G; Santucci R; Gizzi G; Villani V; Cianci M; Miglioli M; Barbara L Effect of vitamin A, C, and E supplementation on rectal cell proliferation in patients with colorectal adenomas. J Natl Cancer Inst, 1992 Jan 1, 84:1, 47-51
  48. Maramag C; Menon M; Balaji KC; Reddy PG; Laxmanan S Effect of vitamin C on prostate cancer cells in vitro: effect on cell number, viability, and DNA synthesis. Prostate, 1997 Aug, 32:3, 188-95
  49. Okunieff P. Interactions between ascorbic acid and the radiation of bone marrow, skin and tumor. Am J Clin Nutr 1991;54:1281S-1283S
  50. Bielory L; Gandhi R Asthma and vitamin C. Ann Allergy, 1994 Aug, 73:2, 89-96; quiz 96-100
  51. Cohen HA; Neuman I; Nahum H Blocking effect of vitamin C in exercise-induced asthma. Vitamin C supplements can also help to reduce exercise induced asthma by reducing airway hyperreactivity. Arch Pediatr Adolesc Med, 1997 Apr, 151:4, 367-70
  52. Heuser G; Vojdani A Enhancement of natural killer cell activity and T and B cell function by buffered vitamin C in patients exposed to toxic chemicals: the role of protein kinase-C. Immunopharmacol Immunotoxicol, 1997 Aug, 19:3, 291-312
  53. Rivas CI; Vera JC; Guaiquil VH; Velásquez FV; Bórquez-Ojeda OA; Cárcamo JG; Concha II; Golde DW Increased uptake and accumulation of vitamin C in human immunodeficiency virus 1-infected hematopoietic cell lines. J Biol Chem, 1997 Feb 28, 272:9, 5814-20
  54. Hemilä H Vitamin C supplementation and common cold symptoms: problems with inaccurate reviews. Nutrition, 1996 Nov, 12:11-12, 804-9
  55. Hemilä H Vitamin C intake and susceptibility to the common cold. Br J Nutr, 1997 Jan, 77:1, 59-72
  56. Hemilä H Vitamin C and common cold incidence: a review of studies with subjects under heavy physical stress. Int J Sports Med, 1996 Jul, 17:5, 379-83
  57. Hankinson SE; Stampfer MJ; Seddon JM; Colditz GA; Rosner B; Speizer FE; Willett WC. Nutrient intake and cataract extraction in women: a prospective study. BMJ, 1992 Aug 8, 305:6849, 335-9
  58. Jacques PF; Taylor A; Hankinson SE; Willett WC; Mahnken B; Lee Y; Vaid K; Lahav M. Long-term vitamin C supplement use and prevalence of early age-related lens opacities. Am J Clin Nutr, 1997 Oct, 66:4, 911-6
  59. Eriksson J; Kohvakka A Magnesium and ascorbic acid supplementation in diabetes mellitus. Ann Nutr Metab, 1995, 39:4, 217-23
  60. Cunningham JJ; Mearkle PL; Brown RG Vitamin C: an aldose reductase inhibitor that normalizes erythrocyte sorbitol in insulin-dependent diabetes mellitus. J Am Coll Nutr, 1994 Aug, 13:4, 344-5
  61. Timimi FK; Ting HH; Haley EA; Roddy MA; Ganz P; Creager MA Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. J Am Coll Cardiol, 1998 Mar, 31:3, 552-7
  62. Eberlein König B; Placzek M; Przybilla B Protective effect against sunburn of combined systemic ascorbic acid (vitamin C) and d-alpha-tocopherol (vitamin E). Am Acad Dermatol, 1998 Jan, 38:1, 45-8
  63. Simon JA; Grady D; Snabes MC; Fong J; Hunninghake DB. Ascorbic acid supplement use and the prevalence of gallbladder disease. Heart & Estrogen-Progestin Replacement Study (HERS) Research Group. J Clin Epidemiol, 1998 Mar, 51:3, 257-65
  64. Gustafsson U; Wang FH; Axelson M; Kallner A; Sahlin S; Einarsson K The effect of vitamin C in high doses on plasma and biliary lipid composition in patients with cholesterol gallstones: prolongation of the nucleation time. Eur J Clin Invest, 1997 May, 27:5, 387-91
  65. Alessio HM; Goldfarb AH; Cao G Exercise-induced oxidative stress before and after vitamin C supplementation. Int J Sport Nutr, 1997 Mar, 7:1, 1-9
  66. Dawson EB; Harris WA; Teter MC; Powell LC. Effect of ascorbic acid supplementation on the sperm quality of smokers. Fertil Steril, 1992 Nov, 58:5, 1034-9
  67. Böhm F et al.Carotenoids Enhance Vitamin E Antioxidant Efficiency. Journal of the American Chemical Society 1997;119:621-622
  68. Watanabe H; Kakihana M; Ohtsuka S; Sugishita Y Randomized, double-blind, placebo-controlled study of the preventive effect of supplemental oral vitamin C on attenuation of development of nitrate tolerance. J Am Coll Cardiol, 1998 May, 31:6, 1323-9
  69. Gerster H. No contribution of ascorbic acid to renal calcium oxalate stones. Ann Nutr Metab, 1997, 41:5, 269-82

Copyright 1998 Bookman Press, Melbourne, Australia. Reprinted from Vitamins, etc. by Nicola Reavley with permission of Bookman Publishing. www.bookman.com.au/vitamins/

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