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Oligonol: Powerful Antioxidants

Powerful Antioxidant from Lychee Fruit and Green Tea

• Supports Healthy Aging

Free radical damage features prominently in the aging process.  Oligonol is a 100% natural super antioxidant that can neutralize free radicals before the damage starts.  A dietary supplement consisting of the world's first oligomerized polyphenols, Oligonol is created using a truly break-through technology that maintains polyphenols as oligomers or "oligomerized" polyphenols.  Scientific research has shown that the bioavailability of the polyphenols in Oligonol is five times greater than typical polyphenols, which means faster absorption, plus a more effective and efficient super antioxidant for the body. 

Research:

Protective effects of oligomers of grape seed polyphenols against beta-amyloid-induced oxidative cell death.

Li MH, Jang JH, Sun B, Surh YJ

Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Shinlim-dong, Kwanak-ku, Seoul 151-742, South Korea.

beta-Amyloid (Abeta) is considered to be responsible for the formation of senile plaques that accumulate in the brains of patients with Alzheimer's disease (AD). There is compelling evidence supporting the notion that Abeta-induced cytotoxicity is mediated through the generation of reactive oxygen species (ROS). Recently, considerable attention has been focused on a wide array of non-vitamin antioxidants present in edible plants that are able to scavenge ROS, thereby protecting against oxidative damage. In this study, we have investigated the possible protective effects of formulated polyphenol oligomers (Oligonol) derived from grape seed extracts on Abeta­induced oxidative cell death. Rat pheochromocytoma (PC 12) cells treated with Abeta exhibited increased accumulation of intracellular ROS and underwent apoptosis, as determined by positive in situ terminal end labeling, decreased mitochondrial membrane potential, and the cleavage of poly(ADP-ribose)polymerase. Oligonal attenuated Abeta-induced cytotoxicity, apoptotic features, intracellular ROS accumulation, and lipid peroxidation and increased the cellular glutathione pool. Moreover, Abeta transiently induced the activation of nuclear factor kappaB in PC 12 cells, which was suppressed by pretreatment with Oligonol.

Oligonol* combines the nutrients from lychee fruit and green tea for a powerful and unusual antioxidant. In this blend, the active polyphenols of lychee and green tea are converted into smaller molecules known as oligomers. This unique process makes the nutrients more bioavailable; they are more quickly absorbed and effective for protecting the cells from free radicals and oxidation, and for inhibition of lipid peroxidation. OLIGONOL® also supports improved circulation and energy, all to help support healthy aging.

Alternative Oligonol spelling: oligonel, olegonol, oligenol, oleginol, oliginol