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Health News Archive 198 - Inflammation
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Stevia Suppresses Inflammation

Stevioside, a non-caloric sweetener isolated from Stevia rebaudiana Bertoni, may suppress harmful inflammation, according to a study published in the February 2006 Journal of Agricultural and Food Chemistry.

Researchers from Mahidol University in Bangkok, Thailand used lipopolysaccharide (LPS) to induce inflammation in a human acute monocytic leukemia cell line (THP-1 cells) and treated the cells with stevioside. At 1 mM, stevioside significantly inhibited LPS-induced release of the inflammatory cytokines tumor necrosis factor alpha and interleukin 1-beta without exerting any direct toxic effects. The researchers concluded the data suggest stevioside attenuates synthesis of inflammatory mediators in LPS-stimulated THP-1 cells.

Source: Chaiwat Boonkaewwan, Chaivat Toskulkao, and Molvibha Vongsakul; Anti-Inflammatory and Immunomodulatory Activities of Stevioside and Its Metabolite Steviol on THP-1 Cells. J. Agric. Food Chem., 54 (3), 785 -789, 2006. 10.1021/jf0523465 S0021-8561(05)02346-0.

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