Resveratrol May Protect Against Alcoholic Fatty Liver Disease

Researchers reported a protective effect for resveratrol against alcoholic fatty liver disease in mice.

Laboratory research has associated alcoholic fatty liver with the inhibition of two signaling molecules, SIRT1 and AMPK, which regulate the liver’s fat metabolism pathways. Dr. Min You and colleagues fed mice low-fat diets supplemented with or without ethanol (alcohol) and/or a low or high dose of resveratrol, and measured the expression of SIRT1 and AMPK in the animals’ livers. They confirmed that resveratrol activated SIRT1 and AMPK in the mice that received alcohol, which prevented fatty liver.

See the resveratrol alcoholic fatty liver disease article citation.

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