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Hyaluronic Acid Center, Neptune Krill Oil & Rejuvenation Science for Doctors

Monday, October 29, 2007

Coenzyme Q10 Reduces Statin-Induced Muscle Pain

Muscle-related side effects occur in as many as 15% of patients taking a statin drug. Various myopathic symptoms have also been reported to occur in people with CoQ10 deficiency.

Statin drugs inhibit the synthesis of Co-Q10, and therefore have the potential to cause CoQ10 deficiency. The results of the present study suggest that drug-induced CoQ10 deficiency is the main cause of muscle symptoms in some patients taking statin drugs. However, the fact that CoQ10 supplementation was effective in only a minority of patients indicates that CoQ10 deficiency is not the only cause of statin-induced myopathy.

Read details of this coenzyme Q10 statin-induced muscle pain study.

Saturday, October 27, 2007

Trace Minerals Beneficial for Burns

Twenty-one patients (mean age, 35 years) with burns on a mean of 45% of body surface area were randomly assigned to receive daily intravenous infusions of either 1) zinc, copper, and selenium, or placebo.

Burn patients have trace mineral deficiencies, due largely to large cutaneous losses of these and other nutrients. The severe depression of immune function seen in burn patients may be due in part to these mineral deficiencies. The results of the present study indicate that intravenous administration of zinc, copper, and selenium can improve clinical outcome in patients with severe burns, including fewer pulmonary infections and better wound healing.

Read details of this trace mineral burn study.

Thursday, October 25, 2007

Fish Oil Enhances Brain Development

DHA plays an important role in brain development.

The fetus is at risk of developing DHA deficiency if maternal intake of DHA is inadequate. Pregnant women in the US and Canada consume significantly less DHA than the 300 mg/day recommended by the National Institutes of Health Workshop on the Essentiality of and Recommended Dietary Intakes for Omega-6 and Omega-3 Fatty Acids. The results of the present study demonstrate that maternal fish oil supplementation during pregnancy can improve the child's eye-hand coordination.

View details on this omega-3 fish oil children's brain development study.

Wednesday, October 24, 2007

Selenium Supplementation Prevents Postpartum Hypothyroidism

Pregnant women who are positive for thyroid peroxidase (TPO) antibodies are at high risk of developing postpartum thyroid dysfunction and permanent hypothyroidism. In previous studies, selenium supplementation decreased thyroid inflammation in patients with autoimmune thyroiditis.

The results of the present study indicate that selenium supplementation during pregnancy and in the postpartum period decreased thyroid inflammation and the incidence of hypothyroidism in women with TPO antibodies.

Read details on this selenium postpartum hypothyroidism stydy.

Tuesday, October 23, 2007

Antioxidants Prevent Preeclampsia

Sixty pregnant Indonesian women with low antioxidant status at eight to 12 weeks of gestation were assigned to receive a preparation containing 13 micronutrients or to be part of a control group. The incidence of preeclampsia was 6.9% in the combination group and 29% in the control group.

The results of the present study confirm that nutrient supplementation can reduce the incidence of this common pregnancy complication.

View details of this antioxidant preeclampsia pregnancy study.

Friday, October 19, 2007

L-Arginine Beneficial for Preeclampsia

The results of this study indicate that the addition of L-arginine to standard therapy prolonged pregnancy in women with preeclampsia, allowed for the use of lower doses of antihypertensive medication, and improved neonatal outcomes.

As a precursor to nitric oxide, L-arginine functions as a vasodilator, which may explain its antihypertensive action in this study. The amount of L-arginine used was relatively low, considering that a typical diet provides at least 5 g/day of this amino acid.

Read details of this L-Arginine preeclampsia in pregnancy study.

Thursday, October 18, 2007

Could Evening Primrose Oil Decrease the Need for Cesarean Sections?

Seventy-one pregnant Filipino women who were nearing term were randomly assigned to receive evening primrose oil (EPO) or placebo for one week.

A measure used to determine whether a woman is likely to have a successful vaginal delivery and whether labor should be induced increased (improved) to a significantly greater extent in the EPO group than in the placebo group.

The results of this study suggest that Evening Primrose Oil may be useful as a cervical priming agent to enhance the success rate for vaginal delivery. Supplementation with EPO might therefore be a useful strategy for decreasing the cesarean section rate.

Read details of this evening primrose oil cesarean section study.

Monday, October 15, 2007

Musculoskeletal Pain Due to Vitamin D Deficiency

Numerous studies over the past ten years have shown that vitamin D deficiency is more prevalent than most doctors realize. Symptoms of vitamin D deficiency include musculoskeletal pain and weakness that may be confused with fibromyalgia or chronic fatigue syndrome. The main contributing factor to vitamin D deficiency is inadequate sunlight exposure.

Treatment in most cases was 300,000 IU of vitamin D3 once a month intramuscularly, plus 1,000 mg/day of calcium and 800 IU/day of vitamin D3 orally. In most cases, symptoms disappeared within one to three months, although one patient needed seven months of treatment.

Sunday, October 14, 2007

Fish Oil for Postpartum Depression

Previous studies have suggested that consuming adequate amounts of long-chain omega-3 fatty acids (i.e., eicosapentaenoic acid and docosahexaenoic acid from fish oil) during pregnancy may reduce the incidence of preterm delivery and enhance the development of the brain and visual system of the fetus. The results of the present study suggest that fish oil may also be useful for treating (and presumably preventing) postpartum depression.

Supplementing with alpha-linolenic acid from flaxseed oil or other vegetable oils may not be as effective as using fish oil, because the capacity of the body to convert alpha-linolenic acid to eicosapentaenoic acid and docosahexaenoic acid is limited.

View details on this omega-3 fish oil for postpartum depression study

Saturday, October 13, 2007

Selenium Prevents Side Effects of Chemotherapy

Compared with no selenium treatment, selenium significantly reduced the mean percentage of peripheral blood neutrophils that had undergone apoptosis on day 8 after chemotherapy and significantly reduced the infection rate following chemotherapy.

The results of the present study demonstrate that high-dose selenium decreased the percentage of neutrophils undergoing apoptosis, thereby helping preserve immune function and decreasing the incidence of chemotherapy-related infections.

View details of this selenium chemotherapy side effect study.

Wednesday, October 10, 2007

Aspartame Causes Cancer in Rats

An aspartame dose-related increase was seen in the incidence of various cancers (including lymphoma/leukemia, transitional cell carcinoma of the renal pelvis and ureter, and malignant schwannoma).

Previous reports have indicated that aspartame ingestion can cause epileptic seizures, migraines, urticaria, eye pain, depression, or fibromyalgia in susceptible people. However, the makers of aspartame should not be dismayed that no self-respecting nutritionist can recommend their product as a sugar substitute. Recent anecdotal evidence that aspartame is an effective ant poison. Read about stevia as an alternative natural sweetener.

View details of this aspartame cancer study.

Tuesday, October 09, 2007

Vitamin E Prevents Side Effects of Chemotherapy

Thirty-one cancer patients receiving six courses of cisplatin, paclitaxel, or both of these drugs were randomly assigned to receive 600 IU/day of vitamin E or no vitamin E (control group) during chemotherapy. Neurotoxicity occurred in 25% of the patients in the vitamin E group and in 73.3% of those in the control group.

The results of the present study indicate that vitamin E supplementation can reduce the incidence and severity of chemotherapy-induced peripheral neuropathy.

Read more on this vitamin E chemotherapy study.

Saturday, October 06, 2007

Folic Acid for Precancerous Lesion

Laryngeal leukoplakia is a precancerous lesion that can progress to laryngeal cancer. Both laryngeal leukoplakia and cancers of the oral cavity, pharynx, and larynx are associated with low plasma folate levels. Major risk factors for the development of these cancers are smoking and alcohol intake, both of which can cause folate deficiency.

The results of the present study suggest that folic acid supplementation can reverse laryngeal leukoplakia and prevent its progression to laryngeal cancer.

View details on this folic acid precancerous lesion study.

Thursday, October 04, 2007

Vitamin K2 Reduces Recurrence of Liver Cancer

Sixty patients with hepatocellular carcinoma resulting from chronic hepatitis C, who were apparently free of cancer after radio frequency ablation therapy or surgery, were randomly assigned to receive 45 mg per day of vitamin K2 (menaquinone-4) or no vitamin K (control group).

These results indicate that supplementation with vitamin K2 significantly reduced the recurrence rate of hepatocellular carcinoma and non-significantly increased the survival rate in patients with a history of hepatocellular carcinoma, secondary to chronic hepatitis C.

Read details of this vitamin K2 liver cancer study.

Wednesday, October 03, 2007

Cooking Method Influences Prostate Cancer Risk

The association between meat intake and prostate cancer risk was examined in 29,361 American men participating in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

High-temperature cooking of meat results in the formation of heterocyclic amines, which can cause prostate tumors in experimental animals. The results of the present study suggest that consumption of heavily cooked meat may promote prostate cancer in humans as well.

High-temperature cooking of meats causes the formation of advanced glycation end products, which appear to play a role in the pathogenesis of cardiovascular disease, renal failure, and inflammation.

View details of this cooking methods prostate cancer risk study.

Tuesday, October 02, 2007

"Fever of unknown origin" caused by food allergy

Between the ages of 21 and 30 months, a girl was seen by 16 doctors for fever of unknown origin and C-reactive protein concentrations of 100-200 mg/L (normal, less than 5 mg/L). Elimination of dairy products and subsequent challenge demonstrated that the fever was due to cow's milk allergy. On a milk-free diet, the C-­reactive protein level normalized within one week, and no further fevers occurred.

Doctors have identified fever for long periods of time (up to eight years in one case) that resolved after identification and avoidance of allergenic foods. Despite these reports, allergy is not mentioned as a potential cause of "fever of unknown origin" in standard medical texts.

View a summary of this fever of unknown origin food allergy study.

Monday, October 01, 2007

Potassium Protects the Heart

Diastolic dysfunction (impaired left ventricular filling) is a common and important, though under-appreciated, cause of heart failure. In one recent study, of 556 unselected patients with heart failure, 55% had a normal left ventricular ejection fraction, indicating that heart failure was almost certainly due to diastolic dysfunction. Patients with diastolic heart failure have mortality rates similar to those with systolic heart failure.

The studies reviewed above suggest that potassium deficiency can contribute to diastolic dysfunction and possibly to systolic dysfunction as well.

Magnesium is required for the intracellular uptake of potassium, so potassium supplementation alone will not correct intracellular potassium deficiency unless magnesium deficiency is also corrected.

Read details on this potassium heart study.