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Hyaluronic Acid Center, Neptune Krill Oil & Rejuvenation Science for Doctors

Friday, June 29, 2007

Probiotics Cut Diarrhea Among the Elderly

Probiotic-containing drinks may help reduce diarrhea among older people receiving antibiotics, reports new research that could offer savings to public health services.

Mary Hickson from Imperial College, London, writing in the British Medical Journal, reports that hospital-bound elderly patients receiving antibiotics experienced 22 percent less cases of diarrhea if taking probiotic drinks.

Between five and 25 percent of patients experience diarrhea, including Clostridium difficile associated diarrhea, as a complication of treatment with antibiotics.

Read details on this probiotics diarrhea study.

Wednesday, June 27, 2007

Men with Low Vitamin B6 Intake Have a Greater Risk of Colorectal Cancer

The July, 2007 issue of the Journal of Nutrition published a report by researchers in Japan that found an association between reduced vitamin B6 intake and an increased incidence of colorectal cancer.

Men whose intake of vitamin B6 was in the top 25 percent of subjects had an approximately 35 percent lower risk of colorectal cancer than men in the lowest quarter. Among men in the lowest 25 percent of B6 intake, drinking more than 150 grams alcohol per week doubled the risk of colorectal cancer compared to men who drank less, however, a greater intake of vitamin B6 reduced this risk.

View details of this vitamin B-6 colorectal cancer study.

Monday, June 25, 2007

Soy Isoflavones Boost Bone Mineral Density in Older Women

Supplementation with the soy isoflavone genistein led to increases in bone mineral density in postmenopausal women.

Genistein decreased levels of bone resorption markers and increased levels of markers of new bone formation, producing a net gain in bone mass after one year and two years.

At the end of the study, BMD at the femoral neck had increased in genistein-supplemented group by an average of 0.035 g/cm2, and decreased by 0.037 g/cm2 in the placebo group.

Read more about this soy isoflavone bone mineral density study.

Sunday, June 24, 2007

Increasing Omega-3 to Omega-6 Ratio Reduces Prostate Cancer Risk

Increasing omega-3 fatty acid levels, and decreasing levels of omega-6, could reduce the risk of prostate cancer risk in individuals with a genetic predisposition to cancer, based on results from a recent animal study.

From birth the mice were randomly assigned to eat one of three diets with differing omega-6 to omega-3 ratios - one to one (high omega-3), 20 to one (low omega-3), or 40 to one (high omega-6). Omega-3 fatty acids are found in flaxseed, fish oil and krill oil.

Mice with the tumor suppressor gene did not develop tumors and had 100 percent survival, regardless of diet. In mice with the gene defect, on the other hand, survival was 60 percent in animals on the high omega-3 diet, 10 percent in those on the low omega-3 diet and 0 percent in those on the high omega-6 diet.

Read details on this omega-3 to omega-6 ratio prostate cancer risk study.

Saturday, June 23, 2007

Green Tea Reduces Colon Cancer Risk 57%

A new study indicates that consuming green tea reduces the risk of developing colorectal cancer in women by up to 57%.

Subjects who regularly drank green tea at the study’s start experienced a 37 percent reduced risk of colorectal cancer compared to subjects who consumed green tea irregularly. Subjects who consistently drank green tea both before the study started and during follow-up surveys experienced a 57 percent reduced risk of colon cancer.

Read green tea colon cancer risk reduction study details.

Friday, June 22, 2007

Flaxseed Arrests Prostate Tumor Growth

Consuming flaxseed can help arrest the growth of tumors of the prostate gland

The study involved men scheduled for removal of the prostate due to prostate cancer. Researchers at Duke University Medical Center assigned four groups of approximately 40 patients each to receive a low fat diet, a low fat diet supplemented with 30 grams ground flaxseed daily, an unsupplemented normal diet, or a normal diet combined with 30 grams ground flaxseed per day for one month prior to surgery.

Men in both groups that received flaxseed were found to have the slowest rate of tumor growth when the prostate tumors were examined following surgery. The omega-3 fatty acids in flaxseed are believed to halt the cellular activity that leads to cancer growth and spread by modifying the ability of cancer cells to clump together or adhere to other cells. Lignans from flaxseed might also help inhibit the ability of tumors to form new blood vessels.

Read details on this flaxseed prostate tumor study.

Thursday, June 21, 2007

Ginseng Relieves Cancer-Related Fatigue

Ginseng may help patients suffering from cancer-related fatigue, according to researchers based at Mayo Clinic, Rochester, NY. Researchers with the North Central Cancer Treatment Group (NCCTG) suggested that patients who take high doses of a form of American ginseng suffer less from fatigue that their peers.

Many cancer patients face extreme fatigue after diagnosis and during treatment and getting more sleep or rest often does not relieve the problem.

Ginseng is typically taken to enhance stamina and reduce feelings of fatigue and physical stress. It is also believed to have an anti-cancer function and has been reported to normalize blood glucose levels, improve insulin sensitivity and reduce the risk of obesity.

View details of this ginseng cancer fatigue study.

Wednesday, June 20, 2007

Risk of Stroke Doubles If Diagnosed with Type 2 Diabetes

Individuals diagnosed with Type 2 diabetes are at double the risk of having a stroke compared to those without diabetes, according to new research from the University of Alberta. It was found that the risk of a stroke is considered high within the first five years of treatment for Type 2 diabetes and more than doubles the rate of occurrence.

“We hope our findings will help to dispel the notion that the risk of stroke occurs only in the long term and will improve the motivation of both patients and health care providers to aggressively control cardiovascular risk factors soon after diagnosis.” said Jeerakathil. Nattokinase has shown potential benefit for stroke prevention.

View details of this diabetes stroke study.

Tuesday, June 19, 2007

Blood Proteins Accurately Identify Colon Cancer

Johns Hopkins scientists have discovered proteins present in blood that accurately identify colon cancer and precancerous polyps.

Using a particular concentration of scaffold-proteins as a marker for disease, the Johns Hopkins team - which did not know the colonoscopy results in advance -- were 100 percent accurate in identifying the 28 existing cancers. Using the same protein markers, investigators also correctly identified 51 of 53 individuals (96.2 percent) with normal colons and 14 of 18 (77.8 percent) people with advanced precancerous polyps

It is interesting to note that in other studies, inflammation has been implicated in all 3 conditions - COPD, cardiovascular disease and osteoporosis, while in separate studies omega-3 fatty acids have demonstrated benefits against all 3 conditions. Krill oil is an excellent source of omega-3 fatty acids.

Read more details on this blood protein predicting colon cancer risk study.

Monday, June 18, 2007

Premature Vascular and Bone Changes Occur in COPD Patients

Patients with chronic obstructive pulmonary disease (COPD) have greater arterial stiffness. The researchers also found that those COPD patients with osteoporosis, a common complication of the respiratory disease, had even greater arterial stiffness. These premature signs of aging may explain why COPD patients are at greater risk for cardiovascular disease.

It is interesting to note that in other studies, inflammation has been implicated in all 3 conditions - COPD, cardiovascular disease and osteoporosis, while in separate studies omega-3 fatty acids have demonstrated benefits against all 3 conditions. Krill oil is an excellent source of omega-3 fatty acids.

Read details on this COPD vascular bone density study.

Sunday, June 17, 2007

Vitamin D Associated with Reduced Cardiovascular Risk

Having higher serum levels of 25-hydroxyvitamin D is associated with a lower risk of hypertension, diabetes, obesity, and elevated triglyceride levels, all risk factors for cardiovascular disease.

Participants whose vitamin D levels were in the lowest one-fourth of the study population had a 30 percent greater risk of hypertension, a 98 percent higher risk of diabetes, more than double the risk of obesity, and a 47 percent greater risk of having high serum triglyceride levels than subjects whose vitamin D levels were in the top 25 percent.

Read details on this vitamin D cardiovascular risk factor study.

Saturday, June 16, 2007

Studies Identify Interactions Between Heart Disease, Kidney Disease

Anemia and other conditions related to chronic kidney disease are independently associated with the risk of cardiovascular disease; conversely, heart disease is associated with a decline in kidney function and the development of kidney disease, according to two reports in the June 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Chronic kidney disease is associated with a wide variety of complications, including anemia (low red blood cell count, or red blood cells that are deficient in oxygen-transporting hemoglobin), nerve pain, bone disease, death and cardiovascular disease. Most patients with chronic kidney disease die of complications from heart disease rather than of kidney failure.

Interesting that the same nutritional supplements support both healthy kidney and cardiovascular function - 81% Positive Response to Coenzyme Q10 Treatment for Chronic Kidney Failure.

See details on these kidney disease, cardiovascular disease interaction studies.

Thursday, June 14, 2007

60% of Male College Students Have High Blood Pressure

University of New Hampshire research finds college students are on the path toward chronic health diseases, exhibiting obesity, high blood pressure, high cholesterol, and inactivity.

Metabolic syndrome, a cluster of five risk factors (high blood pressure, excess abdominal fat, high blood glucose, high triglycerides, and low HDL or “good” cholesterol) that are predictive of future development of heart disease and diabetes, is particularly prevalent in males. Sixty-six percent of males (compared to 50 percent of females) had at least one risk for metabolic syndrome, and eight percent of males had metabolic syndrome.

The vast majority of students – 95 percent of women and 82 percent of men – are not meeting minimal nutrient recommendations for fiber. Women’s intake of the important nutrients iron (23 percent meet recommendations), calcium (33 percent meet bare mimimum recommendations) and folate (32 percent meet recommendations) are remarkably low. Twenty-three percent of men and 34 percent of women participated in less than 30 minutes of activity per day.

The research has enormous public health policy implications. When these students are 40-50 years old, and their parents are 60-80 years old, and everyone is in poor health, who will support them?

View details of this important college student health study.

Tuesday, June 12, 2007

Fish Oil and Moderate Exercise Reduce Heart Disease Risk and Body Fat

Fish oil is a rich source of anti-inflammatory omega-3 polyunsaturated fatty acids - EPA and DHA. Sunflower oil is a rich source of pro-inflammatory omega-6 polyunsaturated fatty acids.

Combining moderate exercise (walking at a good pace for 45 minutes three times a week) and taking 6 gm per day of omega-3 rich fish oil appears to significantly improve cardiac health and lower percent body fat in overweight adults.

The average American dietary ratio of omega-6 to omega-3 fatty acids is approximately 20 to 1. The historic normal level healthy level is reported to be 2:1. In addition to fatty fish and omega-3 supplements, krill oil is another important source of DHA and EPA omega-3 fatty acids.

Read details on this fish oil exercise heart disease and body fat reduction study.

Monday, June 11, 2007

Inflammation Increases Risk of Heart Disease 3X

Men whose blood tests positive for the auto-antibody rheumatoid factor have a three times higher risk of heart disease. This increased risk was similar to that found for the well-known risk factors of diabetes (2.5 times) and high blood pressure (4.4 times). However, rheumatoid factor was not found to increase the risk of heart disease in women.

The findings add more weight to the growing evidence that inflammation is implicated in atherosclerosis - hardening of the arteries.

Another inflammatory marker C-reactive protein has also been linked to the development of ischaemic heart disease in previous studies. Omega-3 fish oil and krill oil have been shown to reduce c-reactive protein 30% over a 3-month period.

View details of this inflammation heart disease risk study.

Sunday, June 10, 2007

Pesticide Use Linked to Brain Cancer

Agricultural workers exposed to high levels of pesticides and people who use them on houseplants appear to have a greater risk of developing brain tumors.

The results show that all agriculture workers exposed to pesticides have a slightly elevated risk of brain tumor, but that agricultural workers exposed to the highest levels have a more than twofold greater risk. This group are particularly likely to develop gliomas - a type of central nervous system tumor. Those in the highest quartile of pesticide exposure have a more than threefold greater risk.

Antioxidant supplement therapies and chelation therapy have proven useful to mitigate pesticide damage.

Read details on this pesticide brain cancer study.

Saturday, June 09, 2007

Low Potassium Increases Long-term Mortality in Heart Patients

New research indicates that patients with heart failure who have low to low-normal serum potassium levels are at increased risk of death.

Of particular concern for clinicians, according to Ahmed, is the link between low potassium and diuretics. Diuretics are a common medication for patients with heart failure, and are known to cause low potassium. A study by Ahmed and his colleagues, also published in the European Heart Journal in June 2006, demonstrated that the chronic use of diuretics may increase long-term mortality, which may in part be mediated by low potassium caused by diuretic use.

Read details of this heart patient potassium mortality study.

Friday, June 08, 2007

Green Tea Reduces UVB-Induced Skin Tumors

Researchers investigated whether epigallocatechin gallate (EGCG) can support the health of sun-exposed skin.

In a meta-analysis, scientists searched the medical literature for studies that investigated the photoprotective efficacy of green tea polyphenols against ultraviolet-induced carcinogenesis known as photocarcinogenesis. The reviewers concluded that oral administration of green tea polyphenols in drinking water or the topical application of EGCG prevents UVB-induced skin tumor development in mice.

The mechanism of action behind green tea’s effects includes the ability to initiate DNA repair and the ability to inhibit the suppressed immunity that occurs after excessive exposure to sunlight.

View details of this green tea UVB-induced skin tumor study.

Wednesday, June 06, 2007

Folic Acid Supplementation Lowers Stroke Risk Up to 29%

Folic acid supplementation can reduce the risk of stroke by up to 29%, conclude authors of an article published in the June 2007 edition of The Lancet.

Researchers found folic acid supplementation reduced the relative risk of stroke by an average of 18 percent. In subgroup analyses, an even greater reduction of risk was seen when the treatment lasted over 36 months (29% less risk); if it reduced the concentration of homocysteine in the blood by more than 20% (23% less risk); or if the patient had no previous history of stroke (25% less risk).

The study also found that in areas that did not already have supplementation through fortified or partly fortified grain, folic acid supplementation decreased the risk of stroke by 25%.

Read details on this folic acid stroke risk reduction study.

Monday, June 04, 2007

Omega-3 Fatty Acids Increase Bone Mineral Density

Increasing omega-3 fatty acid intake in the diet at the expense of omega-6 fatty acids may boost bone health and reduce the risk of osteoporosis later in life.

In the fish oil-supplemented mice, bone mineral density increased significantly in distal femoral metaphysis (DFM) by 20 percent, proximal tibial metaphysis (PTM) by 24 percent and tibial diaphysis (TD) by 15 percent, versus baseline. In comparison, BMD increased only minimally in corn oil-fed mice.

In addition to fatty fish and omega-3 supplements, krill oil is another important source of DHA and EPA omega-3 fatty acids.

View details on this omega-3 fatty acid bone mineral density study.

Sunday, June 03, 2007

Green Tea EGCG Boosts Blood Vessel Health

The heart health reputation of epigallocatechin-3-gallate (EGCG), the main flavanol in green tea, may be due in part to improvement in blood flow through the vessels, according to a clinical trial from the US.

"EGCG acutely improves endothelial function in humans with coronary artery disease, and may account for a portion of the beneficial effects of flavonoid-rich food on endothelial function," wrote study authors in the Journal of the American College of Nutrition.

Supplementation with the green tea extract was found to improve flow-mediated dilation from 7.1 to 8.6 percent

Read details on this green tea EGCG endothelial function study.

Saturday, June 02, 2007

Flavanol Improves Memory

A plant-derived flavanol found in blueberries, tea, grapes and cocoa enhanced memory in mice and could have the same effect on humans, according to research published in the Journal of Neuroscience. The memory improvement increased further when the mice exercised regularly.

Scientists found that when mice were fed the flavanol known as epicatechin and then exercised, they experienced structural and functional changes in the dentate gyrus, a part of the brain involved in the formation of learning and memory. These findings suggested that a diet rich in flavonols could help reduce the incidence or severity of neurodegenerative disease or cognitive disorders related to aging.

Read more on this flavanol memory study.

Friday, June 01, 2007

Omega-3 - Ultra Purity CO2 vs. Molecular Distillation

In the molecular distillation process, omega-3 fish oils are repeatedly raised in temperature to 200°C (390 °F) to concentrate the EPA and DHA and remove contaminants such as pesticides and heavy metals. This temperature cooks the fish oil and appears to alter its molecular structure.

An alternative to molecular distillation is the EFP (Environment Friendly Purified) CO2 distillation process used to concentrate Omega-3 fatty acids at a temperature of 35-50 °C (95 °F to 120 °F). This means that about 400% less heat is used as well as NO hexane. This reduces the chance that Omega-3 fatty acids are destroyed as well as no risk of trans fats.

This particular brand from the European company Minami is considered the gold standard in fish oils because of its concentration, purity, and unaltered molecular structure. It is also encased in fish gelatin softgels, designed to release the EPA and DHA in the intestine rather than the stomach, for greater absorption. It is more expensive per softgel than standard fish oils, but comparably priced based on price per mg of EPA and DHA.

Read more about ultra purity omega-3 fish oil processing - CO2 versus molecular distillation.