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Hyaluronic Acid Center, Neptune Krill Oil & Rejuvenation Science for Doctors

Tuesday, October 31, 2006

Inflammation Predicts Risk for Recurrent Stroke & Mortality

People who have suffered their first ischemic stroke often have elevated inflammatory biomarkers in their blood that indicate their likelihood of having another stroke or an increased risk of dying.

Researchers found that elevated levels of high-sensitivity C-reactive protein (hs-CRP), a test commonly used to predict risk of heart disease, was associated with more severe strokes and an increased risk of mortality.

“A better understanding of biomarkers for stroke risk may lead to the use of treatments to reduce the risk of people suffering debilitating strokes. Omega-3 fish oil and neptune krill oil have proven to reduce biomarkers of inflammation, such as C-reactive protein.

View details of this inflammation stroke and mortality study.

Monday, October 30, 2006

Mother's Folic Acid Supplements Reduce Children's Cancer Risk

A study conducted by Dr. Greta Bunin of California and colleagues at the Children's Hospital of Philadelphia, PA looked at the effects of taking vitamin supplements during pregnancy and the subsequent risk of children developing brain cancer

The mothers of 315 children diagnosed with brain cancer, before the age of six at diagnosis, were compared to 315 similar mothers whose children did not have cancer. It was found that mothers whose children had brain cancer were about half as likely as mothers of well babies to consume higher levels of iron and folate from food and supplements during pregnancy.

View details of this mother's folic acid vitamin intake affects children's cancer study.

Sunday, October 29, 2006

Low Vitamin D Associated With Advanced Breast Cancer

Researchers have found that vitamin D levels are higher in women with early-stage breast cancer compared to women with advanced (locally advanced or metastatic) breast cancer. This indicates that vitamin D deficiency may play a role in breast cancer progression.

The researchers determined that patients with early-stage breast cancer had significantly higher circulating levels of the vitamin D metabolite 25(OH)D concentration of 57 nmol/l compared to those with advanced disease 46.0 nmol/l.

Read details on this vitamin D breast cancer study.

Saturday, October 28, 2006

Vitamin A Important for Gastrointestinal Tract Function in Children

Vitamin A acts as an immune enhancer and anti-inflammatory in the gut of children who are infected with gastrointestinal pathogens such as E. coli, a new study has found.

Researchers investigated the impact vitamin A supplementation has on childhood diarrhea by determining how the vitamin affects the mucosal immune response in the gut.

Vitamin A supplemented children infected with pathogenic Escherichia coli had reduced levels of the inflammatory protein compared with children in the placebo group.

Read details of this children's vitamin E gastrointestinal e. coli study.

Friday, October 27, 2006

Curcumin Reduces Plaque Build-Up in Alzheimer's Patients

Curcumin, the pigment responsible for turmeric’s yellow color, helps immune cells clear out the plaque build-up that is thought to play a role in Alzheimer’s disease, reports a study in the November 2006 Journal of Alzheimer's Disease.

The age of the patient and the stage of the Alzheimer's disease appeared to influence the effectiveness of curcumin. The most benefit occurred in the cells from younger patients and patients with early-stage Alzheimer's. The curcumin appeared to have no effect on the macrophages from the healthy controls.

View details of this curcumin alzheimer's study.

Thursday, October 26, 2006

Omega-3 Fatty Acid Reduces Autism Symptoms

Researchers gave 13 autistic children either 1.5 grams of omega-3 fatty acids per day or placebo for 6 weeks. At the end of the study they used the Aberrant Behavior Checklist (ABC) to gauge the omega-3 fatty acid effectiveness on autistic symptoms.

Researchers found no adverse side effects in either group, however the omega-3 group had significant decreases in hyperactivity and repetitive movements (called steriotypy) compared to placebo. After citing previous research showing benefits on brain function with up to 10 grams of omega-3 fatty acids per day, they found this study to “suggest that omega-3 fatty acids may be effective and well-tolerated in children with autism.”

Read more about this omega-3 fatty acid autism study.

Wednesday, October 25, 2006

L-Arginine Reduces Fat and Waist Circumference

Researchers published a study demonstrating the weight-loss benefits of high doses of the amino acid L-Arginine.

Thirty three obese patients with elevated blood sugar consumed a low-calorie diet and exercised for 21 days. Subjects were then divided into two groups. The first group received 8.3 grams a day of L-arginine; the second group received placebo.

At the end of the study, those who took L-arginine had a statistically significant decrease in adipose fat mass and waist circumference, with statistically significant improvements in mean daily glucose profiles.

Read further results of this l-arginine fat loss and waist reduction study.

Tuesday, October 24, 2006

Fruit and Vegetable Powder Reduce DNA Damage

In this study, researchers evaluated the benefit of a fruit and vegetable powder concentrate on signs of oxidative damage.

By the end of the study, there was a 30% (beneficial) increase in circulating T lymphocytes, and a 40% reduction in DNA damage in white cells in those given fruit and vegetable powder concentrate compared to the placebo group. Overall, it was found that those who consumed the supplement had increased levels of plasma nutrients with improvement in antioxidant capacity and reduction in DNA damage with increase in circulating T cells.

Read details on this fruit vegetable DNA damage study.

Monday, October 23, 2006

Omega-3 Fatty Acid Reverses Minor Memory Loss

Researchers reported that omega-3 fatty acids improved cognitive function in subjects with mild memory loss.

Once you've allowed your cognitive function to decline, it becomes increasingly difficult to reverse the decline. The fact is, by the time you have advanced or severe memory loss, most of your brain cells have died and cannot be revived. However, taking precautionary measures, such as supplementing with omega-3 essential fatty acids, may very well mean the difference between suffering memory loss or not.

Read details on this omega-3 fatty acid alzheimer's disease study.

Sunday, October 22, 2006

Pine Tree Bark Reduces Diabetic Microangiopathy

Diabetic microangiopathy is responsible for major diabetic health complications, such as leg ulcers, kidney failure and retinopathy. A study published in the September edition of Angiology shows that supplementing with Pycnogenol, an antioxidant plant extract from the bark of the French Maritime pine tree, significantly reduced diabetic microangiopathy (DM) in patients.

Diabetic microangiopathy may result in vision loss in diabetic retinopathy, kidney problems and ischemic tissue necrosis causing leg ulcers which may lead to amputation.

When patient’s blood flow was measured in a standing position, pine tree bark treatment improved capillary blood flow by 68 percent, compared to 8 percent in the placebo group.

View details of this pycnogenol pine tree bark diabetic microangiopathy study.

Saturday, October 21, 2006

CLA Helps Maintain Bone Mineral Density

Researchers found that conjugated linoleic acid (CLA) helps maintain bone mineral density in mice, possibly through anti-inflammatory actions. Inflammation exerts a significant influence on bone turnover, inducing the chronic form of osteoporosis. Dietary nutrition has the capacity to modulate inflammatory response. Therefore, nutritional strategies and lifestyle changes may prevent age-related osteoporosis.

Researchers examined CLA’s effect on bone mineral density (BMD) in middle-aged female mice. After 10 weeks, CLA-fed mice maintained a higher BMD in different bone regions compared to corn-oil-fed mice.

Researchers concluded “these findings suggest that CLA may prevent the loss of bone and muscle mass by modulating markers of inflammation and osteoclastogenic factors.”

View details on this CLA bone mineral density study.

Thursday, October 19, 2006

Arthritis Pain Killers Increase Risk of Heart Attack

Two classes of drugs commonly used to treat osteoarthritis – non-steroidal anti-inflammatory drugs (NSAIDs) and COX-2 inhibitors (a newer generation of NSAIDs) – present similar, increased risks of heart attacks while offering about the same level of pain relief, according to a new report by Health and Human Services’ Agency for Healthcare Research and Quality.

Many experts initially expected that COX-2s, which target only the enzyme that stimulates inflammation, would not cause the same stomach problems as traditional NSAIDs. Unexpectedly, the drugs were linked to serious cardiovascular problems.

Alternative remedies for arthritis such as cetyl myristoleate, hyaluronic acid, and natural, highly selective COX-2 pain relievers.

View details of this arthritis pain killer heart attack study.

Tuesday, October 17, 2006

Green Tea Extends Life, Reduces CVD and Stroke

A new study published September 2006 in the Journal of the American Medical Association (JAMA) showed that drinking green tea reduces the risk of all-cause mortality.

Women who drank 5 or more cups of green tea a day had a 23 percent lower risk of all-cause mortality, than those who drank just one cup of green tea a day or less. As well, women who drank 5 cups of green tea had a 31 percent lower risk of dying of cardiovascular disease (CVD) than those who only drank one cup of green tea a day or less. Stroke mortality for women was reduced by an astounding 62 percent.

View details on this green tea cardiovascular disease and stoke study.

Monday, October 16, 2006

Cranberry Juice Effective Against E. Coli Bacteria and UTI's

80% of UTIs are caused by E. Coli bacteria.

A new study published in the February 2006 issue of Biotechnology and Bioengineering, has found that cranberry juice’s effectiveness for UTI’s is not by killing E. Coli bacteria, but by helping prevent the bacteria from attaching to the walls of the digestive tract in the body.

Researchers found that after only three hours, cranberry juice directly affected the bacteria by altering its shape and resulted in an inability to continue binding to the glass. So while the bacteria were not killed by the cranberry juice, they were far less able to bind to the surfaces. When looking at cranberry juice’s role in UTI’s, cranberry juice helps prevent E. Coli from binding to the walls of the bladder.

Read details on this cranberry E. Coli bacteria UTI study.

Sunday, October 15, 2006

Soy Isoflavones Enhance Intestinal Microflora

Soy isoflavone supplementation may stimulate the growth of specific subgroups of intestinal flora, according to a new study.

39 postmenopausal women received isoflavone supplementation with or without a probiotic and prebiotic for two months. Isoflavones alone stimulated growth of microorganisms in the Clostridium coccoides-Eubacterium rectale cluster, Lactobacillus-Enterococcus group, Faecalibacterium prousnitzii subgroup, and Bifidobacterium genus. The effect of increasing species diversity was observed to be long-lasting, particularly with Bifidobacterium.

View details on this soy isoflavone intestinal microflora study.

Saturday, October 14, 2006

Vitamin C Prevents Pregnancy Complication

Premature rupture of the chorioamniotic membranes (PROM) affects 10-20% of all pregnancies. It is the main known cause of preterm delivery and is associated with increased rates of neonatal and maternal morbidity and mortality. Vitamin C plays a role in the synthesis of collagen, which is involved in maintaining the mechanical strength of the chorioamniotic membranes.

The results of the present study indicate that supplementing with 100 mg/day of vitamin D beginning in the 20th week of gestation decreased the incidence of PROM by 74% in Mexican women with borderline-low dietary vitamin C intake.

View details of this vitamin C pregnancy complication study.

Friday, October 13, 2006

Vitamin D3 94% More Potent Than Vitamin D2

Twenty healthy male volunteers were randomly assigned to receive a single 50,000 IU dose of either vitamin D2 (ergocalciferol) or vitamin D3 (cholecalciferol). Similar increases were seen in the serum concentration of the administered vitamins, indicating equivalent absorption.

However, 250HD levels continued to rise in the vitamin D3 group, peaking at 14 days, whereas 250HD levels fell rapidly in the vitamin D2 group and returned to baseline at 14 days. The area under the serum concentration-time curve from day 0 to infinity indicated the potency of vitamin D2 being only 10.6% that of vitamin D3. Conversely, it may be stated that vitamin D3 is 94% more potent than vitamin D2, and this explains the conflicting reports of effectiveness of vitamin D supplementation in prior studies.

Read commentary by Alan Gaby MD on this vitamin D3 vitamin D2 potency study.

Thursday, October 12, 2006

Folic Acid Supplements Reduce Risk of Alzheimer's by 55%

In a 10-year study, researchers evaluated the benefit of taking folic acid against the risk of developing Alzheimer's Disease.

During the 10-year period, 57 people were diagnosed with Alzheimer's. Researchers said those subjects who were getting at or above 400 micrograms of folate per day had 55% lower risk of developing Alzheimer's than those who were consuming less than that amount. The team of researchers also noted that most subjects were able to achieve 400 micrograms or more only by taking a supplement.

View details of this folic acid alzheimer's disease study.

Wednesday, October 11, 2006

DHA in Mother's Milk Increases Infant Psychomotor Skills

At Baylor College of Medicine in Houston TX, 227 mothers were given a 200 mg capsule of DHA or placebo daily for 4 months, beginning 5 days after delivery. DHA and EPA are the two major components of omega-3 fatty acids.

The children of DHA-supplemented mothers scored significantly higher on the Bayley Psychomotor Development Index (PDI), when compared to the children of the non-supplemented mothers. The Bayley PDI assesses fine and gross motor skills such as hand-eye coordination in infants and children.

View details of this omega-3 DHA nursing mother infant psychomotor skill study.

Tuesday, October 10, 2006

CoenzymeQ10 Dramatically Benefits End Stage Heart Failure Patients

A randomized, double blind, placebo controlled trial was recently conducted to measure the effect of Coenzyme Q10 Q-Gel in patients with end stage heart failure.

The results at the end of the twelve week trial were dramatically positive for the use of CoQ10 Q-Gel in patients with congestive heart failure and end stage heart failure. Treatment with Q-Gel for 12 weeks was associated with a significant reduction in left ventricular wall thickness, left ventricular mass, ejection fraction and end diastolic, end systolic volumes and more.

View details of this CoQ10 Q-Gel end stage heart failure study.

Monday, October 09, 2006

DHEA Effective at Reducing Depression in HIV / AIDS Patients

This study was designed to assess the efficacy of dehydroepiandrosterone (DHEA) as a potential treatment for non-major depression in HIV / AIDS patients.

On the basis of clinicians' ratings, DHEA was superior in the intent-to-treat analysis, where the response rate was 56% for the DHEA group versus 31% for the placebo group. In the completer analysis, the response rate was 62% for the DHEA group, compared to 33% for placebo patients. Non-major but persistent depression is common in patients with HIV / AIDS, and the authors of this study believe DHEA may be a useful treatment that is superior to placebo in reducing depressive symptoms.

Read details of this DHEA HIV / AIDS depression study.

Sunday, October 08, 2006

Synbiotics Reduce Risk of Colon Cancer

Synbiotics, a combination of prebiotic and probiotic bacteria, reduce the risk of colon cancer.

In this study, 80 human subjects who either had intestinal polyps (precancerous lesions) removed or had been treated for colon cancer were given placebo or synbiotic daily for 12 weeks.

The synbiotic group showed significantly decreased damage to the cells DNA, compared with those who consumed the placebo. DNA repair was also improved. Another important result was that cell proliferation rate was reduced in the synbiotic group. The results suggest that this synbiotic composition may provide a protective effect against colorectal cancer.

View details of this synbiotic - prebiotic and probiotic - colon cancer risk study.

Saturday, October 07, 2006

Prebiotic Increases Bone Mineral Density 15%

A daily prebiotic supplement, an enriched inulin powder, increased bone mineral density by increasing calcium retention and accretion in bones by 15 per cent after one year.

Previous studies have shown that taking 8g/day of oligofructose-enriched inulin increased the calcium absorbed from the diet by up to 20 per cent.

The new study, at Baylor College of Medicine and the Texas Children's Hospital in Houston, shows a 15 per cent increase of calcium retention and accretion within the bones of the 100 girls and boys, aged nine to 13, after one year of supplementation.

View details of this important prebiotic inulin bone mineral density study.

Friday, October 06, 2006

Inulin FOS Increases Calcium Absorption

Scientists from Brazil have reported that supplementing the diet with the soluble dietary fibers - inulin and fructo- oligosaccharides (FOS), boosted calcium absorption in rats by about 40 percent.

At the end of the intervention period, the researchers reported that calcium absorption in the FOS supplemented group increased by 44 percent, compared to the control diet group. The bone mineral density in the middle of the thigh bone was 0.02 grams per sq. cm greater for the supplemented group, compared to the control diet group.

This selective fermentation pattern results in the production of short chain fatty acids, which increase the acidity in the colon, improving the solubility of the calcium present. The calcium is then better absorbed into the body.

View details of this inulin FOS calcium absorption study.

Thursday, October 05, 2006

Pesticide Exposure Increases Parkinson's Disease Risk 70%

A recent study by researchers at the Harvard School of Public Health in Boston, MA examined the relationship between Parkinson's Disease and pesticide use in over 143,000 people over a 10-year period.

Exposure to pesticides was reported by 7,864 participants (5.7%). People reporting exposure to pesticides were found to have a 70 percent higher incidence of Parkinson's than those without exposure. In an interesting related studies: Vitamin E Alpha-Tocotrienol Helps Maintain Nervous System Health.

View more on this pesticide exposure Parkinson's disease risk study.

Wednesday, October 04, 2006

Aspirin, Ibuprofen and Cox-II Pain Killers Increase Risk of Heart Attack

Cardiovascular side effects aren’t limited to the use of the newer painkillers called COX-2 inhibitors—a category that includes Celebrex and the recently discontinued Vioxx and Bextra. Old standbys, like ibuprofen and aspirin, also increase the risk of heart attack, reports the October 2006 issue of the Harvard Heart Letter.

Researchers have determined that use of a COX-2 inhibitor increases the chances of having a heart attack. Vioxx, which was taken off the market because of possible heart complications, may lead to or worsen heart failure—but so can traditional NSAIDs, such as aspirin and ibuprofen. In general, cardiovascular side effects are most likely to happen in people with existing heart disease or those at high risk for it.

Read details on this aspirin ibuprofen and COX-2 heart attack warning from Harvard University Medical Center.

Tuesday, October 03, 2006

Omega-3 Fatty Fish Cuts Kidney Cancer Risk

Eating omega-3 rich fatty fish at least once a week lowered women's risk of renal cell carcinoma, while lean fish and crustaceans - shrimp and lobster - offered no benefit, explaining the inconsistent results of previous studies analyzing total fish consumption.

The study found that women who ate fatty fish once a week or more had a 74% reduction in developing abnormal cellular growth within the kidneys compared to those who didn't eat any fish at all. Women who consumed one or more servings of fatty cold-water fish per week had a 44% decreased risk of renal cell carcinoma compared with women who ate no fish.

Read details of this omega-3 fatty fish kidney cancer study.

Monday, October 02, 2006

Curcumin Blocks Colorectal Cancer Inducing Hormone

Curcumin, the pigment responsible for the yellow color of the spice turmeric, has been found to block the activity of a hormone associated with the development of colorectal cancer.

Hormonal management is a new method of cancer treatment or prevention identified in this study. A gastrointestinal hormone called neurotensin has been linked to the production of an inflammatory protein that accelerates the growth of a variety of cancer cells.

"Our findings suggest that curcumin may be useful for colon cancer treatment, as well as potential colon cancer suppression, in cells that respond to this gastrointestinal hormone, neurotensin," said Dr. Mark Evers, senior author and director of UTMB's Sealy Center for Cancer Cell Biology.

Read details of this colorectal cancer hormone blocking curcumin study.

Sunday, October 01, 2006

Omega-3 Awareness Low in Pregnant Women

The majority of women surveyed know the importance of including folic acid and calcium with vitamin D in their diet, but half of them do not know about the need for DHA Omega-3, a critical nutrient for the development and health of a baby’s brain, heart and eyes.

A growing body of scientific evidence continues to demonstrate that DHA Omega-3 is an important building block of perinatal nutrition. Often overlooked by mothers and health care providers alike, it is possibly the most important nutrient expectant mothers don’t know about. If taken during pregnancy, it may help lower the risks of pre-term birth and even post-partum depression. DHA Omega-3 is also important for ongoing health throughout life.

View more information on this pregnant women omega-3 awareness study.