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Hyaluronic Acid Center, Neptune Krill Oil & Rejuvenation Science for Doctors

Tuesday, January 31, 2006

Chromium Picolinate Reduces Carb Cravings

Over a period of eight weeks, a randomized, double-blind, placebo-controlled study was conducted in subjects with atypical depression to assess the effects of carbohydrate cravings. Carbohydrate cravings, weight gain and unexplained fatigue are characteristic symptoms of atypical depression.

The chromium picolinate group in the evaluable populations showed significantly greater improvements in four HAM-D-29 items: carbohydrate craving, appetite increase, increased eating, and diurnal variation of feeling.

Read further details on this Chromium Picolinate Carb Cravings Reduction Study

Monday, January 30, 2006

Memory and Problem Solving Enhanced with Adequate Zinc

In the study, 209 seventh graders - 111 girls and 98 boys - consumed four ounces of fruit juice containing 0, 10, or 20 mg of zinc each school day for 10-12 weeks.

Adolescents who drank orange juice packed with 20 mg of zinc performed better on memory and attention exercises compared to those whose diet was not supplemented and youngsters who received the minimum daily recommended 10 mg per day.

How profound that the minimum daily recommended dose of 10 mg of zinc keeps an adolescent from dying or disease directly attributable to zinc deficiency. However it is only adequate to help your children become mediocre competitors when it comes to mental performance.

Read the details on this zinc study in adolescents.

Sunday, January 29, 2006

Vitamin E Tocopherols Reduce Alzheimer’s Risk

Mixed vitamin E tocopherols may offer greater protection against Alzheimer’s disease than vitamin E alone, according to a recent report in the American Journal of Clinical Nutrition.

The vitamin E family consists of four tocopherols and four tocotrienols. Alpha tocopherol is the most common form of vitamin E found in dietary supplements, while gamma tocopherol is the most prevalent form in food. Researchers have previously noted that vitamin E from food sources, but not from supplements, is associated with a reduced risk of Alzheimer’s.

The study results underscore the importance of daily supplementation with vitamin E and indicate that mixed vitamin E tocopherols may offer greater protection against common diseases of aging such as Alzheimer’s than alpha tocopherol alone.

Read more on this Vitamin E Alzheimer study.

Saturday, January 28, 2006

Berry Extracts Help Prevent Ulcers

Berry extracts help kill the bacteria that cause most ulcers and improve the efficacy of prescription ulcer therapy, according to a report from Creighton University in Omaha, NE.

The Nebraska researchers demonstrated that berry extracts not only inhibit the growth of H. pylori, but also render it more susceptible to clarithromycin, one of the antibiotics used to eradicate the bacteria. H. pylori bacteria were incubated with extracts of raspberry, strawberry, cranberry, elderberry, blueberry, or bilberry, or with a combination of all six berries.

All of the berry extracts inhibited H. pylori growth and increased its sensitivity to clarithromycin better than controls. The combined extracts exhibited greater potency than did the individual berry extracts.

Read more on Berry extracts that help prevent ulcers.

Friday, January 27, 2006

Carotenoid supplements reduce DNA damage

The results of a double-blind study published in the January 2006 issue of the American Journal of Clinical Nutrition revealed that postmenopausal women given mixed carotenoids or single carotenoids had less damage to their DNA than those administered a placebo over an eight week period. Carotenoid supplements contained beta-carotene, lutein and lycopene.

By the fifteenth day of the study, there was significantly less endogenous DNA damage among women who received mixed carotenoids or beta-carotene alone compared to that measured at the beginning of the study. By the study's conclusion all groups who received carotenoid supplements showed less hydrogen-peroxide induced DNA damage, and significantly less endogenous DNA damage compared to presupplementation levels.

Read further study results here.

Thursday, January 26, 2006

49% of Men over 40 Have Erectile Dysfunction

Among 3921 Canadian men aged 40 to 88 years seen by primary care physicians, Grover and colleagues found that the prevalence of erectile dysfunction (ED) was 49.4%. Independent risk factors associated with ED included the presence of cardiovascular disease, diabetes, and increasing 10-year Framingham coronary risk scores or fasting blood glucose levels.

Newly published study results, as detailed in The Hardness Factor, by Steven Lamm, MD, show a combination of L-Arginine and Pine Bark Extract to be effective for the improvement of erectile function.

Read more study information or information on The Hardness Factor.

Wednesday, January 25, 2006

Inflammation Predicts Cancer Death

A higher white blood cell (WBC) count, a marker of inflammation, is associated with a greater risk of dying from cancer.

In a population of 3,189 participants in the Blue Mountains Eye Study, by the end of the study, there were 212 cancer deaths. Men and women whose white blood count was in the top 25 percent of the study population with greater than 7,400 cells per microliter had a 73 percent higher risk of dying of cancer than those whose white blood cells were in the lowest 25 percent at 5,300 cells or less.

The authors conclude, "Our findings suggest that local inflammatory processes that have long been known to be associated with tumor progression may be reflected in the systemic inflammatory marker of higher WBC count."

Further study details here.

Tuesday, January 24, 2006

Hyaluronic Acid Absorption and Bioavailability

BioCell Technology LLC, the exclusive suppliers of BioCell Collagen II released results in April 2003 from a double-blind clinical study proving that the naturally occurring Hyaluronic Acid (HA) in BioCell Collagen II has significant peak absorption and steady state bioavailability in normal volunteer subjects.

In a 36-hour peak absorption study using a single dose, BioCell Collagen II hyaluronic acid significantly increased in the blood in four hours and peaked at a level 7008.62% above control in twelve hours (P=0.05).

These results are in contrast to previous published studies, which your Doctor is more likely to have heard about, which showed that other HA forms (such as the ones which are injected into joints) are not orally absorbed and thus unavailable for use by the human body.

Read further study results here.

Monday, January 23, 2006

Vitamin D Reduces Precancerous Polyps

In the December 2005 edition of the journal Cancer, a study on colon polyps, frequently precursors of colon cancer, was reported. Of the nineteen participants, eleven were given calcium carbonate 1500 mg, plus vitamin D3 400 IUs, three times daily, whereas the rest were given placebo for six months. It was found calcium plus vitamin D resulted in tissue changes that may have contributed to reduce polyp formation.

Read further study details.

Sunday, January 22, 2006

Vitamin D Signals to Prevent Bone Loss During Osteoporosis

The risk of bone fracture resulting from falls increases as we age due to bone loss and osteoporosis. Physicians have routinely prescribed calcium, vitamin D and vitamin D–related drugs to retard bone loss, but until now, little was known about how vitamin D enhances bone.

Researchers identified a new vitamin D–related compound (DD281) that could prevent bone loss more potently than the natural vitamin D. These findings clarify how vitamin D helps limit bone resorption in conditions such as osteoporosis, and suggest that synthetic vitamin D analogs, including DD281, may warrant clinical trial to asses their potential in the treatment of osteoporosis and other related disorders of bone resorption.

Read study details here.

Saturday, January 21, 2006

Homocysteine Up, Bone Mineral Density Down, Fractures Up

Elevated homocysteine levels have long been recognized as a risk factor for heart disease. Recently, however, research is pointing to the role for homocysteine in other areas of our health. A January 2006 study confirms that high homocysteine levels have an adverse effect on bone health.

The Norwegian researchers determined that the higher the plasma levels of total homocysteine, the greater the incidence of low bone mineral density among middle-aged and elderly women. Subjects with the highest homocysteine levels had an approximately two-fold higher risk of a fracture compared to those who had the lowest levels. This same association was not seen among men, an interesting outcome that could explain why women are at a far greater risk of this disease. Women with the lowest plasma folate level also had the lowest BMD.

Read more about this study.

Friday, January 20, 2006

Hyaluronic Acid Enhances Skin Elasticity

A January 2006 bioassay report states the effectiveness of BioCell Collagen II(r) with hyaluronic acid (HA) in inhibiting hyaluronidase. This hyaluronidase enzyme degrades hyaluronic acid, a glycosaminoglycan extracellular matrix constituent which can contribute to signs of aging on the skin.

Hyaluronic acid is found in varying levels in the dermis. Variations in levels account for natural skin alterations associated with aging, such as decreased turgidity, less support of microvessels, wrinkling, and altered elasticity. By inhibiting hyaluronidase, levels of hyaluronic acid in the skin can increase, reducing wrinkling while enhancing natural collagen production.

Read more about this report.

Thursday, January 19, 2006

Ginkgo May Help Prevent Alzheimer’s

A preliminary study suggests that Ginkgo biloba leaf extract may help prevent Alzheimer’s disease. Ginkgo has long been known to improve brain (cognitive) function in adults and to favorably influence other signs of aging.

In Alzheimer’s disease, certain proteins in the brain degenerate to form plaques and deposits of debris known as amyloid. A major component of these plaques and amyloid deposits is called amyloid beta-peptide. It is not known why amyloid beta-peptide forms in brain tissue, although some researchers suspect that environmental exposure to aluminum is an important factor. Any treatment that inhibits amyloid beta-peptide formation is expected to help prevent Alzheimer’s disease.

Read more study details here.

Wednesday, January 18, 2006

Resveratrol inhibits myeloma cell growth

Because resveratrol is reported to display antitumor activities on a variety of human cancer cells, researchers investigated the effects of this natural compound on myeloma and bone cells. They found that resveratrol reduces dose-dependently the growth of myeloma cell lines by a mechanism involving cell apoptosis.

Researchers concluded, taken together, these results suggest that resveratrol or its derivatives deserve attention as potential drugs for treating multiple myeloma.

Read further study details here.

Tuesday, January 17, 2006

Soy Lowers Blood Sugar, Insulin in Postmenopausal Women

Soy isoflavones, a type of phytoestrogen, lowers fasting blood glucose and insulin levels in postmenopausal women, according to a study conducted at the National Taiwan University Hospital.

Taiwanese researchers found that modest amounts of soy isoflavones are as potent as conjugated estrogen in lowering blood glucose and insulin levels.

Soy isoflavones appear to protect against aberrant glucose metabolism in postmenopausal women. By lowering blood glucose and insulin levels, soy isoflavones may help protect against metabolic syndrome and diabetes.

Find study details here.

Monday, January 16, 2006

1 of 8 Forms of Vitamin E Kills Prostate Cancer Cells

Gamma tocopherol, a member of the vitamin E family, helps kill prostate cancer cells, according to a recent report in the Proceedings of the National Academy of Sciences.

In a study conducted at the Children’s Hospital Oakland Research Institute in California, the addition of gamma tocopherol to prostate cancer cell cultures not only inhibited cell proliferation but also caused cell death.

The vitamin E family comprises eight structurally related forms, all of which are potent antioxidants. They are alpha, beta, delta and gamma - tocopherols and tocotrienols. Alpha tocopherol is the most abundant form of vitamin E in the human body and in nutritional supplements, while gamma tocopherol dominates dietary sources.

Read more study details here.

Sunday, January 15, 2006

CoQ10 Counters Harmful Side Effect of Statin Drugs

An adverse effect on cardiac function caused by a cholesterol-lowering medication can be reversed with coenzyme Q10 (CoQ10) supplementation, conclude researchers in Illinois and Texas. 71 percent of individuals using the statin drug atorava-statin (Lipitor®) experienced dysfunctional left ventricular diastolic function that was improved using supplemental CoQ10.

While statin therapy may be indicated for some individuals with abnormal cholesterol profiles, this and other studies indicate that 1) with such a high rate of side effects, one must ensure that statin therapy is absolutely required, and 2) supplemental CoQ10 may help preserve cardiac function during prescription drug therapy.

Read more on this and related studies here.

Saturday, January 14, 2006

New Prescription Drug Recommendation for Everyone

We just came across this prescription drug advertisement. We recommend it as reading for everyone. Look carefully at the lifestyle picture. Enjoy!

Panexa

Improved Pregnancy Rates with L-Carnitine Plus Acetyl L-Carnitine

A 2004 double-blind placebo controlled study of men's fertility demonstrated that L-Carnitine and Acetyl L-Carnitine significantly increased sperm concentration, motility and morphology in men with poor sperm quality, resulting in a significantly higher pregnancy rate.

Naturally achieved pregnancy rates vs placebo = 21.8% vs 1.7% for placebo. (p<01)

Most pregnancies occurred after 6 months on therapy.

Click here for more study information and a pregnancy chart.

Friday, January 13, 2006

MSM Reduces Arthritis Pain

The results of a randomized, double-blind, placebo-controlled trial indicate methylsulfonylmethane (MSM) can improve osteoarthritis pain in the knee.

Researchers studied 50 men and women, 40-76 years of age, who had osteoarthritis knee pain. Compared to the placebo, MSM produced significant decreases in pain and physical function impairment. MSM also produced improvement in performing activities of daily living when compared to placebo.

Read further study details.

Thursday, January 12, 2006

Flaxseed Converted into Omega-3s in Human Body

Consumption of flaxseed oil can increase concentrations of certain omega-3 fatty acids in the human body—good news for vegetarians who will not consume fish or fish oil.

Flaxseed oil contains alpha-linolenic acid (ALA), an Omega-3 fatty acid. There has been some doubt as to whether the human body is able to convert it to longer-chain omega-3 polyunsaturated fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in sufficient amounts. A sufficient amount of EPA and DHA is desirable because EPA and DHA support the heart, brain, retina, pregnancy, lactation and seniority.

According to the researchers, “This study demonstrates the efficacy of the conversion of ALA to EPA and DPA in a minority population with chronic disease, but not DHA. ALA may be an alternative to fish oil for people adverse to consuming fish.”

Read study details here.

Wednesday, January 11, 2006

Chromium Polynicotinate Benefits Blood Sugar, Lipids

Chromium, a trace mineral that is often deficient in adults, may help to prevent or treat metabolic problems, including obesity, glucose intolerance, and unhealthy lipid profiles, according to Georgetown University researchers.

Niacin-bound chromium supplementation may reduce the risk for glucose intolerance, prevent the progression of glucose intolerance to frank diabetes, improve glucose control in diabetics, and assist in managing elevated triglyceride levels.

Study details may be found here.

Tuesday, January 10, 2006

Curcumin Impedes Breast Cancer Metastasis

A study found that curcumin, a substance in the spice turmeric, prevents breast cancer from spreading to the lungs of mice given the compound.

Researchers injected 60 mice with human metastatic breast cancer cells. When the tumors reached the size of 10 millimeters, they were surgically removed. Upon examination of the animals’ lungs five weeks after removal of the tumors, 96% of the mice in the control group had visible metastases. While paclitaxel alone elicited a modest reduction in visible metastases, curcumin produced a significant reduction, and the combination of curcumin and paclitaxel prevented the macrometastases entirely.

Read further study results here.

Saturday, January 07, 2006

Relora® Significantly Reduces Stress, Anxiety and Sleep Latency

Revealing the results of a new study, Next Pharmaceuticals, Inc. announced today that their proprietary botanical ingredient Relora® (which is a blend of Magnolia officinalis and Phellodendron amurense extracts) significantly reduces anxiety, stress and sleep latency in women who suffer from these problems. The new findings were presented at the WorldNutra Conference.

“Up until now, there was no natural formulation that has shown such results in reducing anxiety,” added Garrison. “People who have used Relora, appreciate it as an effective formula that helps them deal with the increasing tension in their lives.”

Read study details here.

Friday, January 06, 2006

Vitamin D Supplementation During Pregnancy Could Reduce Osteoporosis In Children

Vitamin D supplementation of pregnant women could lead to long-lasting reduction in osteoporotic fractures in their children, according to a study published in The Lancet. The study shows that children whose mothers were lacking in vitamin D during pregnancy grow up to have weaker bones.

Women who took vitamin D supplements and women who were exposed to higher levels of sunshine in pregnancy were less likely to be deficient in vitamin D. Sunlight helps the body to make its own vitamin D.

Read more on this study.

Thursday, January 05, 2006

Popular heartburn drugs linked to diarrhea and colitis

People on popular prescription heartburn drugs — Prilosec, Prevacid and Nexium — seem more prone to getting a potentially dangerous diarrhea caused by the Clostridium difficile infection, new research shows. C-diff, as it’s known, can cause severe diarrhea and colitis, a crampy intestinal inflammation. Thus report scientists in December 2005 in the Journal of the American Medical Association (JAMA).

Proton pump inhibitors include Prevacid and Prilosec and the H2 blocker agents include Tagament, Pepcid and Zantac. Along with increasing your risk of C-diff infection, they significantly reduce the amount of acid you have, inhibiting your ability to properly digest food. Reduction of acid in the stomach also diminishes your primary defense mechanism for food-borne infections and will increase your risk of food poisoning.

In a related article, prophetically posted yesterday: Artichoke Reduces Heartburn Naturally

Read more on this JAMA study.

Wednesday, January 04, 2006

Artichoke Reduces Heartburn Naturally

This study aimed to assess the efficacy of artichoke leaf extract in the treatment of patients with heartburn.

The artichoke leaf extract preparation tested was significantly better than the placebo in alleviating symptoms and improving the disease-specific quality of life in patients with heartburn.

Read more here.

Tuesday, January 03, 2006

Beta Glucan Improves White Blood Cell Health after Radiation

Beta glucan enhanced the survival rate and improved the white blood cell recovery rate in mice exposed to radiation, a recent study in the journal Blood reports.

The current study sought to confirm past findings as well as to identify Beta 1, 3-D glucan’s mechanism of action.

When beta glucan was given orally it significantly enhanced the survival of animals receiving a lethal dose of radiation after stem cell transplantation. Forty days following radiation exposure, approximately 30 percent of mice treated with beta glucan survived compared with only 3 percent of the untreated animals.

Read more about this study on Beta Glucan.

Monday, January 02, 2006

Antioxidants Substantially Lower Macular Degeneration Risk

The Journal of the American Medical Association published a study showing that individuals whose diets contain high amounts of the antioxidants beta-carotene, vitamin C, vitamin E and zinc have a significantly lower risk of developing age-related macular degeneration (AMD) than people whose diets contain lower levels of the nutrients. The Age-Related Eye Disease study (AREDS) found that supplements containing 5 to 13 times the recommended daily allowance of these nutrients slowed the progression of the disease.

Dietary levels of beta-carotene, vitamins C and E, and zinc from both food and supplements that were above the median of the total participants' intake were associated with a 35 percent lower risk of age-related macular degeneration.

Further study information is here.

Sunday, January 01, 2006

Pine Tree Bark Helps Hypertension

A study conducted at the University of Arizona Health Sciences Center in Tucson shows that pycnogenol, an extract of French maritime pine bark (Pinus maritima) may lower blood pressure in mildly hypertensive patients.

In a randomized, double-blind, placebo-controlled study, researchers gave pycnogenol to mildly hypertensive patients for eight weeks. Patients were in Stage 1 hypertension—a systolic blood pressure range of 140-159 mmHg, and/or diastolic blood pressure range of 90 to 99 mmHg. Pycnogenol reduced the systolic blood pressure to 134 mmHg and diastolic blood pressure to 94 mmHg in study participants.

Study details here.