Vitamin D Signals to Prevent Bone Loss During Osteoporosis

The risk of bone fracture resulting from falls increases as we age due to bone loss and osteoporosis. Physicians have routinely prescribed calcium, vitamin D and vitamin D–related drugs to retard bone loss, but until now, little was known about how vitamin D enhances bone.

Researchers identified a new vitamin D–related compound (DD281) that could prevent bone loss more potently than the natural vitamin D. These findings clarify how vitamin D helps limit bone resorption in conditions such as osteoporosis, and suggest that synthetic vitamin D analogs, including DD281, may warrant clinical trial to asses their potential in the treatment of osteoporosis and other related disorders of bone resorption.

Read study details here.