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Hyaluronic Acid Center, Neptune Krill Oil & Rejuvenation Science for Doctors

Saturday, December 31, 2005

Quercetin Is Promising for Chronic Prostatitis

Quercetin, a naturally occurring bioflavonoid found in apples, black tea, and onions, was tested as a treatment for chronic prostatitis in a nonblinded study by researchers at the Institute for Male Urology in Encino, Calif. In the trial, an encouraging 59 percent of the subjects improved.

The researchers put 15 category III prostatitis patients on a twice-daily dose of 500 mg quercetin and 15 on placebo for one month. In the quercetin group, symptom scores decreased significantly, by an average of about 40 percent, compared to an insignificant decrease of 6 percent for those taking placebo.

Read about a follow-up study showing even better results using Quercetin activated with Bromelain.

Friday, December 30, 2005

Quercetin Reverses Oxidative Damage in Diabetic Rats

Quercetin blocks free radical damage in diabetic rats, indicating it may prevent the development of tissue injury seen in diabetics, researchers reported in the October 2005 Journal of Nutrition. Both experimental and clinical studies have produced evidence that suggests oxidative stress caused by free radicals is involved in the development and progression of diabetic tissue damage.

The researchers concluded that quercetin “may block the production of noxious mediators involved in the development of early diabetes tissue injury and in the evolution of late complications.”

View more information on this animal study.

Thursday, December 29, 2005

Green Tea Supports Ovarian Health

In the recent epidemiological study, published in the December 2005 Archives of Internal Medicine, researchers investigated the association between green tea consumption and risk of ovarian cancer in 61,057 women aged 40 to 76.

During an average follow-up of 15 years, 301 incident cases of invasive epithelial ovarian cancer developed. The study authors determined that the higher the consumption of either green or black tea, the lower the risk of ovarian cancer. Subjects who drank two or more cups per day had a nearly 50 percent reduction in risk. Each additional cup of tea per day was associated with an 18 percent lower risk of ovarian cancer.

Read further study results here.

Wednesday, December 28, 2005

Gamma-Linolenic Acid Cuts Levels of Breast Cancer-Causing Gene

Gamma-linolenic acid (GLA), a substance in evening primrose oil, borage oil, and several other plant oils, inhibits action of Her-2/neu, a cancer gene that is responsible for almost 30 percent of all breast cancers, Northwestern University researchers report.

Lupu and co-investigator Javier Menendez showed that treating cancer cells that overexpressed Her-2/neu with GLA not only suppressed protein levels of the oncogene, but also caused a 30- to 40-fold increased response in breast cancer cells to the drug HerpetinTM (trastuzumab), a monoclonal antibody that is used for the treatment of many women with breast cancer.

Read more study commentary here.

Sunday, December 25, 2005

Ibuprofen-like activity in extra-virgin olive oil

Newly pressed extra-virgin olive oil contains oleocanthal — a compound whose pungency induces a strong stinging sensation in the throat, not unlike that caused by solutions of the non-steroidal anti-inflammatory drug (NSAID) ibuprofen.

We show here that this similar perception seems to be an indicator of a shared pharmacological activity, with oleocanthal acting as a natural anti-inflammatory compound that has a potency and profile strikingly similar to that of ibuprofen. Although structurally dissimilar, both these molecules inhibit the same cyclooxygenase enzymes in the prostaglandin-biosynthesis pathway.

Read further information on this study.

Saturday, December 24, 2005

Antiviral effect of catechins in green tea on influenza virus

Polyphenolic compound catechins (epigallocatechin gallate (EGCG), epicatechin gallate (ECG) and epigallocatechin (EGC)) from green tea were evaluated for their ability to inhibit influenza virus replication in cell culture and for potential virus killing effect.

Among the test compounds, EGCG and ECG were found to be potent inhibitors of influenza virus replication in cell culture and this effect was observed in all influenza virus subtypes tested.

In a related study, researchers concluded that the anti-viral activity of EGCG manifests itself through several mechanisms, both outside and inside the cell, but at effective concentrations well above that reported in the serum of green tea drinkers.

More study results here.

Friday, December 23, 2005

Pine Tree Bark Treats Venous Ulcers, Precursor to Varicose Veins

A study involving patients who supplemented with the pine tree bark extract known as Pycnogenol® (pic-noj-en-all) may offer an important solution to the difficult treatment of venous ulcers and lends further understanding to the improvement of blood circulation.

Over a six-week period, researchers found in the group treated with Pycnogenol tablets the ulcer size was reduced to just 11.6 percent of the original size – a startling difference from the placebo group. And, the group who supplemented with Pycnogenol and used the topical Pycnogenol powder resulted in complete healing of the ulcer.

“For the first time a highly significant improvement of the ulcer healing process in lower legs was documented. We could obtain definite wound closing within 6 weeks in the patient group who orally and topically supplemented with Pycnogenol,” said Dr. Rohdewald.

Read more about the study here.

Thursday, December 22, 2005

Omega-3 Reduces Risk of Arrhythmia and Sudden Death

A new study revealed that consuming fish oil capsules helped prevent the decline in heart rate variability associated with airborne particulate matter.

"Fish oil as a source of omega-3 polyunsaturated fatty acids could be considered as a potential form of preventive measure to reduce the risk of arrhythmia and sudden death in elderly subjects exposed to ambient air pollution," Dr. Holquin, the lead author stated. Dr Holguin explained the findings: "In this randomized controlled trial, fish oil supplementation prevented the reduction in heart rate variability associated with the same-day exposure to indoor particulate matter.

Read further study results here.

Wednesday, December 21, 2005

Study Finds N-Acetyl Cysteine Helps Reduce Cocaine Cravings

A 2005 study funded by the National Institutes of Health (NIH) suggests that N-Acetyl-Cysteine, a common over-the-counter supplement, can reduce the cravings associated with chronic cocaine use. This research is among the first to identify N-acetylcysteine (NAC) as a potential agent to modulate the effects of cocaine addiction. There is also early evidence in animal models of addiction to suggest that this chemical works similarly in the treatment of heroin addiction, and possibly alcoholism.

"Cocaine is highly addictive and can have devastating effects on the health and well being of users," says lead researcher Peter Kalivas, Ph.D., Professor and Chair of the Department of Neurosciences at the Medical University of South Carolina (MUSC). "The discovery that a readily available supplement can reduce the intense cravings associated with cocaine use is an important finding for individuals undergoing treatment for cocaine addiction. Reduced craving might help addicted individuals restrain from abusing cocaine."

Read more study results here.

Tuesday, December 20, 2005

Aged Garlic Helps Prevent Atherosclerosis

Research at the UCLA Medical Center has further confirmed the power of using garlic extracts to help prevent heart disease. Plaque in the lining of blood vessels impedes blood flow and can result in heart attack and stroke. As the plaque increases, it impedes blood flow and can result in heart attack and stroke.

Earlier in 2005, researchers from around the world presented research at the American Heart Association meeting in Washington, DC that showed that garlic powder not only reduces calcification of the arteries, but also reduces plaque formation by up to 40 percent.

Read more on this and a prior study.

Monday, December 19, 2005

Save $5.6 Billion in Health Care Costs with Omega-3 and Lutein

A 2005 study has determined that supplementation with Omega-3 fatty acids and lutein with zeaxanthin could save American senior citizens $5.6 billion in health care costs during the next five years. To receive your share of the savings, keep reading.

The Lewin Group analyzed hundreds of studies conducted over the last 30 years on omega-3. They concluded that an 1,800 mg daily dose of omega-3 could reduce coronary heart disease in people over age 65, resulting in 384,303 fewer hospitalizations over the next five years and a consequent $3.1 billion savings in health care expenditures.

Seniors who take 6 to 10 mg a day of lutein with zeaxanthin could reduce their susceptibility to age-related macular degeneration (AMD), The Lewin Group found. During the next five years, that would result in 98,219 fewer people losing their independence because of advanced AMD, saving $2.5 billion in caregiving costs.

Save your health and your share of $5,600,000,000.

Sunday, December 18, 2005

Selenium Up, Mortality Down

A study was recently published in the journal Clinical Chemistry defining the association between plasma selenium levels and increased risk of mortality in an elderly population between the ages of 73 and 83.

A significant association was found between those individuals with low plasma selenium levels and increased mortality rates by an amazing 54 percent. In addition, when the underlying causes of death were considered, we found an association with cancer-related mortality.

More study information is here.

Saturday, December 17, 2005

Acetaminophen Leading Cause of Liver Failure Death update

"Acetaminophen poisoning has become the leading cause of acute liver failure in the United States," report the authors of a new study in the December 2005 issue of Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD). Tylenol is the leading brand name for acetaminophen.

Sixty-three percent of patients who overdosed accidentally had been using prescription narcotic/acetaminophen compounds, often referred to as Tylenol #3 or Tylenol #4, containing acetaminophen plus codene. Thirty-eight percent had been using two acetaminophen medications simultaneously.

Some patients reported taking less than 4 grams of acetaminophen per day before falling ill. Four grams of acetaminophen can be obtained from taking 8 - 500 mg Tylenol capsules per day, the maximum recommended dose. "Our data suggests that there is a narrow therapeutic margin and that consistent use of as little as 7.5 g/day may be hazardous," report the authors.

Tylenol is effective for discomfort due to inflammatory and non-inflammatory pain. If you want to treat inflammatory pain without harming your health, the following supplements are useful: For chronic arthritis pain relief with no side effects consider Cetyl Myristoleate. Other inflammation reducers include: Omega-3 fish oil, Bromelain, and Boswellia.

More information on the study and alternatives which reduce inflammation which reduces the pain.

Wednesday, December 14, 2005

81% Positive Response to Coenzyme Q10 Treatment for Chronic Kidney Failure

Ninety-seven patients (mean age, 48 years) with chronic renal failure (serum creatinine > 5 mg/dl), with a history of declining renal function for at least 12 weeks, were randomly assigned to receive, in double-blind fashion, water-soluble coenzyme Q10 (CoQ10; 60 mg, 3 times per day orally) or placebo for 12 weeks.

The number of patients receiving dialysis decreased from 21 to 12 in the CoQ10 group, and remained unchanged at 24 in the placebo group (p < 0.02). Eighty-one percent of the patients receiving CoQ10 had a positive response to treatment.

These results suggest that CoenzymeQ10 can improve renal function and reduce the need for dialysis in patients with chronic renal failure. The public-health implications of this study are enormous, considering that chronic renal failure is a serious and debilitating disease and that the annual cost of dialysis in the United States is more than $22 billion.

Read further study results here.

Tuesday, December 13, 2005

Vitamin D Protects Your Heart

A new study has linked a lack of sunshine, the body's most natural source of vitamin D, to the prevalence of cardiovascular disease (CVD).

There are a number of physiological mechanisms triggered by vitamin D production through sunlight exposure that act to fight heart disease, according to the study:
  • An increase in the body's natural anti-inflammatory cytokines.
  • The suppression of vascular calcification.
  • The inhibition of vascular smooth muscle growth.

Read the study abstract here.

Monday, December 12, 2005

Glucosamine Improves Symptoms in Mouse Model of Multiple Sclerosis

Using a mouse model of Multiple Sclerosis (MS) in an animal study, Glucosamine dramatically delayed the onset of symptoms and improved the animal's ability to move and walk.

In a scientific article, Norwegian researchers investigated the therapeutic effect of Glucosamine on Experimental Autoimmune Encephalomyelitis (EAE), an animal model of MS. It was demonstrated that oral or intravenous administration of glucosamine significantly reduced acute EAE, with reduced inflammation of the Central Nervous System (CNS).

Read more here.

Sunday, December 11, 2005

Vitamin D Helps Treatment-Resistant Asthma

Asthma patients who don't respond to steroid treatment suffer repeated asthma attacks, and are at greater risk of dying from the condition. Researchers from King's College London have found that vitamin D3 could substantially improve the responsiveness of these patients to steroid treatment, offering them hope of an improvement in their condition.

The researchers found that when vitamin D3 was added in the lab, the previously steroid-resistant cells were able to respond to the treatment by producing IL-10 to the same extent as T-cells taken from steroid-responsive patients.

Dr Catherine Hawrylowicz, who led the King's research team said: 'The hope is that this work will help those people who are on heavy doses of steroids to reduce the amount of medication they are taking.'

Read more information on initial testing in human patients.

Saturday, December 10, 2005

Magnesium and Vitamin B6 for Kidney Stone Prevention

149 patients with longstanding recurrent idiopathic calcium oxalate and mixed calcium oxalate/calcium phosphate renal stones received 100 mg of magnesium oxide 3 times a day and 10 mg of pyridoxine (vitamin B6) once a day for 4.5 to 6 years. The mean rate of stone formation fell by 92.3%, from 1.3 stones per patient per year prior to the study to 0.10 stones per patient per year during the study. No significant side effects occurred.

The results strongly suggest that supplementing with modest doses of magnesium and vitamin B6 can greatly reduce the recurrence rate of calcium oxalate kidney stones. Another uncontrolled study demonstrated that supplementing with 500 mg/day of magnesium (without vitamin B6) also reduced stone formation by about 90%.

Read more commentary on the study.

Thursday, December 08, 2005

Acetaminophen Leading Cause of Liver Failure Death

Scientists are warning about the risks posed by acetaminophen after it emerged the painkiller had become the leading cause of liver failure in the US. The annual proportion of cases caused by paracetamol - known in the US as acetaminophen - had risen from 28% in 1998 to 51% in 2003, researchers said. Tylenol is the leading brand name for acetaminophen.

A number of alternatives now exist. For chronic arthritis pain relief with no side effects also consider Cetyl Myristoleate. See Minor Pain Comfort, a natural COX-II inhibitor, for all natural relief from minor pain associated with occasional tension, stress and over-exertion.

Read more about this Acetaminophin study here.

Sunday, December 04, 2005

Silicon: A Wrinkle Smoothing Bone-Builder

Dr Nicholas Perricone MD reports that Silicon, a trace mineral found in connective tissue, is essential to maintaining a firm structural foundation for skin. Last year, Belgian researchers presented the exciting results of a controlled clinical trial in women aged 40 to 65. After taking a biologically active form of silicon called choline-stabilized orthosilicic acid (ch-OSA) for five months, the women-all of whom suffered from sun-damaged or prematurely aged skin-enjoyed substantially shallower micro-wrinkles and improved skin elasticity.

And, the results of a new study presented at the American Society for Bone and Mineral Research (ASBMR) conference suggest that ch-OSA improves the bone health benefits of both calcium and vitamin D. Dr Perricone suggests that you look for the BioSil brand to make sure that it is in an absorbable form and take in conjunction with calcium and Vitamin D for optimum effect.

Sorry, he does not cite his references.

Saturday, December 03, 2005

"Perricone Weight Loss Diet" Airs on PBS-TV

Don't miss Dr. Nicholas Perricone's all new PBS-TV television special, titled "The Perricone Weight Loss Diet", which will air coast to coast throughout December.

In this program, Dr. Perricone explains the inflammation-obesity connection, and unveils exciting new information about foods, beverages, nutritional supplements, and lifestyle choices with proven ability to accelerate weight loss by increasing metabolism, metabolizing fat, building and maintaining muscle mass and eliminating food cravings.

For more information on Dr Pericone's new Perricone Weight-Loss Diet book and recommended supplements, click here. Please check your local listings for your local viewing schedule.

Chromium Polynicotinate Increases Lifespan 20%

Chromium nicotinate, also known as chromium polynicotinate, is a patented oxygen-coordinated, niacin-bound chromium. Commonly used for weight-loss, it demonstrated its ability to prolong the life span of test animals by more than 20 percent.

In the study, rats prone to many of the manifestations of aging were fed diets containing Chromium polynicotinate, which increased their average life span by 22 percent compared to rats fed the same diet without chromium polynicotinate. Rats fed chromium polynicotinate also experienced lower systolic blood pressure, lower circulating glucose levels, and a trend toward lower, normalized hemoglobin levels, a long-term indicator of blood sugar status.

Read more study details here.

Friday, December 02, 2005

Lung Cancer Reduced 90% with Omega-3 Fatty Acids

“In 2000 he was told by his doctor he had only a few months to live with terminal lung cancer,” said Pardini, a professor of biochemistry and associate director of the Nevada Agricultural Experiment Station at the University of Nevada, Reno. “But five years later, he is still alive, and has even gained a little weight.”

The cancerous tumors found in D.H.’s lungs have shrunk to 10 percent of what they were in 2000, according to 2004 computed tomography (CT) scans. What worked with DH is not a common medical treatment such as chemotherapy or surgical excision. It was a nutritional intervention, drastically increasing the patient’s intake of omega-3 fatty acids, which are often found in fish oil.

So far, though, most studies in this country are limited to animal models, but a case study about D.H., which was published in the recent issue of the Nutrition and Cancer journal, could be a major step forward for human clinical trials.

Read more about this lung cancer case here.

Magnesium Intake Inversely Related to Colon Cancer Risk

Researchers believe that dietary magnesium may play a role in the prevention of colorectal cancer based on animal studies, but data in humans is lacking. To evaluate the hypothesis that a high magnesium intake may reduce the risk of colorectal cancer, researchers evaluated a population-based cohort of 61,433 women aged 40 to 75 years without previous diagnosis of cancer at baseline from 1987 to 1990.

This population-based prospective study suggests that a high magnesium intake may reduce the occurrence of colorectal cancer in women.

Read further study information here.

Thursday, December 01, 2005

N-Acetyl Cysteine Slows Lung Decline in Pulmonary Fibrosis

N-acetyl cysteine, a precursor of the antioxidant glutathione, slows the deterioration of lung function in patients being treated for idiopathic pulmonary fibrosis. Idiopathic pulmonary fibrosis is a chronic progressive interstitial pneumonia whose cause is unknown, although an oxidant-antioxidant imbalance may contribute to the disease process.

The authors writing in the New England Journal of Medicine in November, 2005 concluded that adding 600 milligrams acetyl cysteine three times daily to a regimen or prednisone and azathioprine helps preserve lung function in idiopathic pulmonary fibrosis patients better than drug therapy alone. "High-dose acetylcysteine in addition to standard therapy is," they write, "therefore, a rational treatment option for patients with idiopathic pulmonary fibrosis."

Read more study details here.